Welcome to ECF, Matt...
Remember to provide equipment information when asking for build recommendations... without it, respondents are completely in the dark. As you've provided wire type and gauge, the remaining info needed would be: what atty, what wick material, what current output device, and in your case, where it is a determining factor in vapor density & volume... what PG/VG juice blend.
The amount of power output you have at your disposal will determine how low a resistance, what wire gauge, coil net surface area and build type would perform well.
For example... if you have 100 watts, (standard mech Ohm's law calculation - 23.8 amps at 4.2V)... you can build down to 0.17Ω. With 100 watts, you can build a 22 gauge, dual parallel atomizer that produces a heat flux (radiant coil heat) of 324 mW/mm² and a coil surface area of 150.34 mm² per coil.
As available wattage goes down, (numeric) wire gauge should go up... to maintain a reasonable temperature and heat dwell time. For every wattage value, there is a small selection of optimal wire gauge/net resistance/coils in parallel for that wattage... that provides best coil surface area and range of desirable temperature.
Available air flow effects choices as well. Too little air flow and low resistance can become problematic, in that heat absorption and transfer can become dangerous for the device, battery and user.