I noticed a difference in taste between temp control and watts control but that may have only to do with how the wire heats, not the chemical makeup of the wire. Regardless, do any of these various wires leach any of their material into the vapor in quantities that bear on health concerns. At 450 degrees and 30 max watts, my usual vape, my guess is no. I keep the power down for a bunch of reasons including concerns like this.
Leech Quantities to cause health concern...I presume not.
You are moderating your mg & ml intake and are cautious about the heat flux
and are utilizing temperature control...you are one of the safer operators.
There were times if you recall some flavors used to be tank crackers !
Flavors breaking the tanks without any extra ordinary heat being applied....
if it was mentioned a year before it was happening no one would have thought
a still liquid can react with tanks innards so drastically.
Wire's do react with liquid ...one just has to look at the coil gunk.
The difference in vape btw temp and watt / volt control will influence the wire and also the cotton / silica / hemp / rayon / SS Mesh whichever acts as the wick and does influence the
flavor profile....slow cooked food tastes much better than food cooked in a furnace.