I de-wick both HV and LR 306s... I use Ikenvape HV and Cisco low-res. I leave the bridge alone on both.
The wick may not cause an issue immediately, but eventually they get funky... sometimes leaving the wick there causes an issue right from the start.
The first time I used an HV 306, all I got was burnt taste... de-wicked it, and it was bliss!
Besides, the wick is only there for foam cartridge users... which I am not : )