Each time you open that bottle to dump the so called bad juices don't you get the moisture and air into the bottle and for long time, the juices are more diluted and loosing nic level( assuming you are using same level nic)
Moreover, some juices when mixed together some juices breakdown the flavour and sometime it also produces a residue at the bottom of the mixed bottle juice
Why not mix a small bottle of different flavour to try out new flavour.
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