Ever read this?
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Very interesting. Never even thought nicotine's 'addictive' properties would be an issue ever again.
It's interesting, thanks. 
Just skimming it superficially, I don't agree with a few things, particularly,
"Nicotine does not propel itself to the top of the individual's motivations nor does it impair the ability of natural rewards to motivate behavior."
and
"With addictive substances, behavioral compensation occurs following changes in unit dose... No such apparent regulation of intake has generally been seen with nicotine."
Just skimming it superficially, I don't agree with a few things, particularly, "Nicotine does not propel itself to the top of the individual's motivations nor does it impair the ability of natural rewards to motivate behavior."
and
"With addictive substances, behavioral compensation occurs following changes in unit dose... No such apparent regulation of intake has generally been seen with nicotine."
It's interesting, thanks.
"Nicotine does not propel itself to the top of the individual's motivations nor does it impair the ability of natural rewards to motivate behavior."
and
"With addictive substances, behavioral compensation occurs following changes in unit dose... No such apparent regulation of intake has generally been seen with nicotine."
What's not to agree with?
<RED TEXT> A ...... addict will will risk life in jail to rob a gas station so they can fund their addiction. How many burglaries happen because someone "just needed $10 for cigarettes?!
<BLUE TEXT> Again, compared to ......, an addict will NEED a certain dosage to feel satisfied....example, 2 ml injection to get "high" would be normal for John Doe, but if you only give him 1.5 ml injection, his body will know the difference. Whereas as smoker only needs "a cigarette"...nicotine content in analogs is a limited variable. For example, my pack of analogs shows 1.2 - 2.7 mg/cigarette. A consumer never knows if that analog they just stood outside in the freezing cold to have, had 1.2 mg...or 1.8....or the top limit of 2.7 mg, but we feel satisfied. Therefore, his comment can mean "a nicotine addiction does not need a "specific dose" to make the user/consumer feel better."
Okay, here are my counter-points.
There have long been robberies for cigs and smash & grabs have become steadily more common as the price has been jumping the past decade. Cigarettes are a lot easier to get than ...... though. I know, I've given out hundreds of single cigarettes to folks who ask me on the street or at the mall or the office or... And I've asked for them too.
People go through their garbage for butts, get dressed and go out at 3am to get them, request handouts from strangers, zone out on whatever is being said waiting to leave and have that ciggie, tear the house apart trying to find the extra pack.... Middle class folks who are aghast at law breaking have found themselves sneaking cigs across the border and trying to find underground cheap sales online.
People say they can't have even one if they want to stay quit - that isn't normal.
Most here wouldn't put up with the ecig industry as it exists now, otherwise.
Dose: Within a tiny range true... but we see here people being quite unsatisfied and calling FAIL until they find the proper dose. Pharma NRT is mostly ineffective, in part due to dose. Most of all, it's been shown that people alter the way they smoke regular commercial cigarettes in order to access a certain dosage of nic - they puff lighter or deeper or handle the filter differently or hold smoke longer. They do compensate, it's been measured.
Okay, here are my counter-points.
get dressed and go out at 3am to get them, request handouts from strangers, zone out on whatever is being said waiting to leave and have that ciggie, tear the house apart trying to find the extra pack..
been there,, lol
now sometimes its a panic to check and make sure the extra batteries are charging,,
I puff on 0mg carts while driving to/from work now. I used to smoke 5 analogs on that same 45 min drive....and I only started vaping a week ago.
Maybe it is more the physical motions/sensations that are addictive, and not the nicotine
I think all they're really saying is that nicotine doesn't get you as high as ....... :/
haha.
I don't know, I have such a short attention span that depending on what time of day it is or what's on my mind, at a time such as now if I read it I am just laughing my ... off because it's a bunch of words I know that make absolutely no sense together. And I'm able to read them consecutively fluidly, but cannot derive any sense or meaning or even understand how I'm reading it at all.
=(
Also, when I was staying at the hospital for a while, a nurse informed me that there were more nicotine receptors in your brain than there were for any other drug. But then someone said that "all your receptors can fit ......." and I was like okay..... what am I supposed to believe?
It's physically addicting as well as psychologically.
haha.
I don't know, I have such a short attention span that depending on what time of day it is or what's on my mind, at a time such as now if I read it I am just laughing my ... off because it's a bunch of words I know that make absolutely no sense together. And I'm able to read them consecutively fluidly, but cannot derive any sense or meaning or even understand how I'm reading it at all.
=(
Also, when I was staying at the hospital for a while, a nurse informed me that there were more nicotine receptors in your brain than there were for any other drug. But then someone said that "all your receptors can fit ......." and I was like okay..... what am I supposed to believe?
It's physically addicting as well as psychologically.
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We in the US have bought heavily into the biological side of addictive behavior. I hate to break it to you, but there are NO irrefutable studies that indicate a genetic disposition to addiction. As such, looking at the drug itself is insufficient to indicate its level of addictive potential. Don't forget, some kids get strung out on sniffing Sharpies! The chemical only functions in combination with the behavior. Additionally, associations and expectations play a large role in how addicted we become. Most of us associate smoking with positive social interactions, drinking, a relaxing stroll, a nice break during a hard day's work, etc. And we expect our smoke breaks to be relaxing. I cannot stand the useless direction so much research seems to take in regards to these issues.
On a psychopharmacologic note, nicotine imitates acetylcholine in the brain, and its possible that this peptide functions differently in humans than in animal test subjects.
Cheers,
-Mickey
On a psychopharmacologic note, nicotine imitates acetylcholine in the brain, and its possible that this peptide functions differently in humans than in animal test subjects.
Cheers,
-Mickey
People who study adopted and separated twins would beg to disagree. In fact adopted vs. not altogether.
As this is tangential to the point of the discussion, I am going to mostly leave this alone. And I don't feel like going through my books and getting reference after reference. But please believe, I have spent many hours researching this topic and read both point and counterpoint.
I am not saying genetics do not play a role in addiction, but genetic determinism is just plain silly. Even height depends approximately 20% on environmental factors (early childhood diet, etc). If genetics cannot explain something as simple as height, how could it hope to encompass something as complicated as addiction?
Addiction is multiaxial. Genetic determinism attempts to override the emotional underpinnings of addictive issues.
Okay, then I misunderstood your statement "there are NO irrefutable studies that indicate a genetic disposition to addiction."
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