Harvard Eliquid Study Today

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VNeil

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But this isn't the first issue facing eCigs and plausibly isn't the last. So, someone like you, who's more or less convinced there is a significant problem with inhaling diketones at the levels that eliquid products provide, could perhaps straighten out (according to your view) with people you directly interact with and who might have questions that go beyond the article. Me, I'd be telling them they are inhaling far more diketones via smoking and even there we haven't seen any known cases of actual harm, specifically tied to diketones.

Then there's the people who likely think there are more dangers to come / be reported on. You and I can't answer that (now) for them. So, better to go with the danger they do know than the one they don't, is how I'm sure they reconcile the return to smoking.

As a dual using person, I can understand why go back given the anti-vaping rhetoric that is around and that even some vapers naively accept as gospel.



This be the gospel of which I speak. We also know it has been a non-issue in all forms of smoking/vaping. That is what we know DeAnna.
It is both amazing and dismaying that so many people are so willing to totally ignore a simple observational fact: smokers have been inhaling, on a daily basis, far more diketones than popcorn workers and even more so than typical vapers and even the most extreme vaper. For up to 40 years or more. With no evidence whatsoever of "flavor related disease".
 

crxess

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Very wrong diagram. Extremely misleading.
"Harvard study worst offender" - it is value for 1 ml of juice. Current vaper easily vapes 20+ ml/day, so this value should be multiplied by 20. Result is close to smoking.
So: with wrong juice a vaper can consume as much of diacetyl as a smoker.

Is it dangerous? May be not. I do not know. But I would not tell other people it is "100 times better than smoking" in terms of diacetyl consumption.

Not sure where your DREAM NUMBERS come from, but the Vast majority of Vapers doubtfully exceed 4-5ml per day.
I personally use extremely productive equipment and Vaping almost ALL DAY(18 HOURS) barely crack 20ml
Currently Disabled so:
No Work
No home Projects
No going where vaping is restricted
No Diversions

i.e. ECF & Vaping is my(temporary) Norm

Do Not attempt Stupid ANTZ Tactics without PROOF!!!

Cigalikes
Ego's/Clearos
Kayfuns on 15w setups
Are still flying off the shelves.

Sure, there is a Sub group of Intense Vapers, but that is absolutely not the norm or what Vaping as a whole represents.

Yea, you ...... me off. :grr:
 
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crxess

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Whooo, okay.............So over that :D
Got a little cranky :lol::lol::lol:

Great Read
{ Earlier this month, Harvard released a study suggesting at least one aspect of vaping might be as detrimental as traditional smoking. Researchers at the university found that 75 percent of flavored e-cigs contained a chemical called diacetyl, commonly used in artificial butter flavorings. While safe to eat, the dangers of inhaling diacetyl were revealed in the early 2000s, when workers at several popcorn factories came down with a condition that became known as "popcorn lung," an irreversible scarring of the lungs that causes shortness of breath and fits of coughing. The Harvard study led to the inevitable haunting headlines, some of which were testament to how little many in the media actually understand about the perils of tobacco smoking. "Flavored E-cigarettes May Be Worse For You Than Nicotine" declared Mother Jones, reinforcing the misguided notion that nicotine, present in all forms of vaping and tobacco smoking, is the leading scourge. While studies like Harvard's are critical to fully understanding e-cigs, they too often have the opposite effect. Tobacco cigarettes, for instance, have also long been known to contain diacetyl — at levels over 100 times those found in electronic cigarettes — yet earlier tobacco studies found that even these levels were not enough to cause popcorn lung in smokers.}

Read more: E-Cigs' Inconvenient Truth: It's Much Safer to Vape
 

Nimaz

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These results were already published a few years ago. No surprise in their findings whatever the details are. They were just looking at compounds which are likely to be there in the first place and what a surprise, they found them. These researchers need to renew their grant money... smart enough to trigger media reactions over a front topic of heath, financial and political importance. Scientifically redundant, fairly uninteresting and certainly non-challenging, flavor concentrates are available without Diacetyl, Acetoin, or Acetyl Propionyl. I started DIY because I couldn't find out what was in the commercial juices I was using w/o knowing the specific compound to avoid yet. Sadly, many ejuices manufacturers seem careless to avoid these expectantly attackable compounds in their consumables making... The vaping industry should strive to make our products as healthy as possible. Although many vaping companies do, the BT also get the picture and published results showing that products like the blu ecig are toxic free... I am guessing that the BT is just waiting to pull out the their mass product vaping gears when the vaping industry will struggle to fit the upcoming regulations. BT will look as the good guys. I'm so sad and disappointed....
 
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DeAnna2112

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These results were already published a few years ago. No surprise in their findings whatever the details are. They were just looking at compounds which are likely to be there in the first place and what a surprise, they found them. These researchers need to renew their grant money... smart enough to trigger media reactions over a front topic of heath, financial and political importance. Scientifically redundant, fairly uninteresting and certainly non-challenging, flavor concentrates are available without Diacetyl, Acetoin, or Acetyl Propionyl. I started DIY because I couldn't find out what was in the commercial juices I was using w/o knowing the specific compound to avoid yet. Sadly, many ejuices manufacturers seem careless to avoid these expectantly attackable compounds in their consumables making... The vaping industry should strive to make our products as healthy as possible. Although many vaping companies do, the BT also get the picture and published results showing that products like the blu ecig are toxic free... I am guessing that the BT is just waiting to pull out the their mass product vaping gears when the vaping industry will struggle to fit the upcoming regulations. BT will look as the good guys. I'm so sad and disappointed....

You nailed some good points here...this is pretty much how i see things unfolding and why. The vaping industry is the first to cry but always the last to be on top of anything when it hits the media...and it's not that they didn't know or see it coming. Very frustrating. It would be nice to for once to see them on the front lines addressing things before other sources pick it up and cover it.
 
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englishmick

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It is both amazing and dismaying that so many people are so willing to totally ignore a simple observational fact: smokers have been inhaling, on a daily basis, far more diketones than popcorn workers and even more so than typical vapers and even the most extreme vaper. For up to 40 years or more. With no evidence whatsoever of "flavor related disease".

Making popcorn, smoking, and vaping, all rather different. Coming at us in different ways. Airborn dust, smoke, vapor. Mixed or in solution with different carriers. Hot, cold, warm. Steady continuous exposure, intermittent high exposures to hot vapor or smoke with breaks in between.

I don't think we can go from a handful of cases of BO in popcorn workers to saying smoking or vaping are likely to be dangerous. Neither can we go the other way and say that because smoking DK's hasn't led to large outbreaks of BO that vaping the stuff is safe. Or that because supposed cases in popcorn workers appeared within a couple of years that five years of BO-free vaping proves there's no danger. The only bit of what I see as reliable evidence is that rats or in-vitro tissue exposed to very high levels of the stuff show consequences. But there's a big gap between that and vaping in the real world.

We have very little information. I see no justification for confidently believing that vaping DK's is either safe or not safe. That's not going to matter to unprincipled people who are looking for ammunition to shut vaping down. But it should matter to us.

A lot of these threads seem to be based on "proving" by debate and analogies and reductio arguments and so forth that it is either safe or not safe. We all have to make decisions based on our best judgement, or best guess.
 

Alien Traveler

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Not sure where your DREAM NUMBERS come from, but the Vast majority of Vapers doubtfully exceed 4-5ml per day.
I personally use extremely productive equipment and Vaping almost ALL DAY(18 HOURS) barely crack 20ml
Currently Disabled so:
No Work
No home Projects
No going where vaping is restricted
No Diversions

i.e. ECF & Vaping is my(temporary) Norm

Do Not attempt Stupid ANTZ Tactics without PROOF!!!

Cigalikes
Ego's/Clearos
Kayfuns on 15w setups
Are still flying off the shelves.

Sure, there is a Sub group of Intense Vapers, but that is absolutely not the norm or what Vaping as a whole represents.

Yea, you ...... me off. :grr:
Read ECF threads named something like "how much juice do you vape daily" and you'll see that today many people exceed 20 ml/day consumption.
Take a look at B&M's, on their stock: they are catering to high volume vapers.
Yes, cigalikes still own the market (I believe it's around 60%), but I believe there are millions of 20+ ml vapers (not too educated guess, but nevertheless...)
 

Alien Traveler

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We're making progress. You are owning up to you statement. Now explain why only a comparison to about the most extreme vaping discussed here (20ml per day) is acceptable to you, and any other vaping style, no matter how common out in the world at large, is unacceptable. Do you consider yourself the Final Arbitor in all vaping comparisons?
I read it trice. Still cannot find logic...
 

mattiem

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It is both amazing and dismaying that so many people are so willing to totally ignore a simple observational fact: smokers have been inhaling, on a daily basis, far more diketones than popcorn workers and even more so than typical vapers and even the most extreme vaper. For up to 40 years or more. With no evidence whatsoever of "flavor related disease".
And to me it is both amazing and dismaying that so many people right here are not hearing what you are saying :facepalm: Thank you for having the patients to continue saying it. I, for one, am hearing you.
 

Jman8

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Making popcorn, smoking, and vaping, all rather different. Coming at us in different ways. Airborn dust, smoke, vapor. Mixed or in solution with different carriers. Hot, cold, warm. Steady continuous exposure, intermittent high exposures to hot vapor or smoke with breaks in between.

I don't think we can go from a handful of cases of BO in popcorn workers to saying smoking or vaping are likely to be dangerous. Neither can we go the other way and say that because smoking DK's hasn't led to large outbreaks of BO that vaping the stuff is safe. Or that because supposed cases in popcorn workers appeared within a couple of years that five years of BO-free vaping proves there's no danger. The only bit of what I see as reliable evidence is that rats or in-vitro tissue exposed to very high levels of the stuff show consequences. But there's a big gap between that and vaping in the real world.

We have very little information. I see no justification for confidently believing that vaping DK's is either safe or not safe. That's not going to matter to unprincipled people who are looking for ammunition to shut vaping down. But it should matter to us.

A lot of these threads seem to be based on "proving" by debate and analogies and reductio arguments and so forth that it is either safe or not safe. We all have to make decisions based on our best judgement, or best guess.

IMO, this assertion is on par with saying "I see no justification for confidently believing that vaping (nicotine) is safer or less safe than smoking."

In current reality, we are set up to argue (for / against) the idea that vaping diketones is potentially dangerous unless proven otherwise. How is that not applicable to every other ingredient/compound in vaping? And then how is that not applicable to every aspect of life?

i.e. Science (over the long term, aka 3000 years) is potentially more dangerous than religion. Prove otherwise.
 
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VNeil

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IMO, this assertion is on par with saying "I see no justification for confidently believing that vaping (nicotine) is safer or less safe than smoking."

In current reality, we are set up to argue (for / against) the idea that vaping diketones is potentially dangerous unless proven otherwise. How is that not applicable to every other ingredient/compound in vaping? And then how is that not applicable to every aspect of life?

i.e. Science (over the long term, aka 3000 years) is potentially more dangerous than religion. Prove otherwise.
Science never attempts to prove a negative. That is the philosophy of propaganda
 

VNeil

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Read ECF threads named something like "how much juice do you vape daily" and you'll see that today many people exceed 20 ml/day consumption.
Take a look at B&M's, on their stock: they are catering to high volume vapers.
Yes, cigalikes still own the market (I believe it's around 60%), but I believe there are millions of 20+ ml vapers (not too educated guess, but nevertheless...)
The members of this forum are far, far removed from the average vaper I meet in the wild. That is an observational fact. This forum attracts extremists. And despite that, the majority of members here that discuss their juice consumption consume far far less.
 

Alien Traveler

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The members of this forum are far, far removed from the average vaper I meet in the wild. That is an observational fact. This forum attracts extremists. And despite that, the majority of members here that discuss their juice consumption consume far far less.
1. B&Ms are attracting extremists also?
2. ECF attracts attention of newbies, so we shall not lie, even for the sake of vaping.
 
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skoony

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Read ECF threads named something like "how much juice do you vape daily" and you'll see that today many people exceed 20 ml/day consumption.
Take a look at B&M's, on their stock: they are catering to high volume vapers.
Yes, cigalikes still own the market (I believe it's around 60%), but I believe there are millions of 20+ ml vapers (not too educated guess, but nevertheless...)
Two can play this game. I read the forums too. A solid 80% of vapers use regular ego type bats and
or VV/VW set ups with clearo's or cigalikes. The 20% using higher end high powered mods are mostly duo-
users. They use more standard gear along with their big set up. The small percentage of exclusive high
powered only users do not use 20 ml or more on a day to day basis. Those that do vape 20 ml or more
on a daily basis are by far a very small percentage. They tend towards high VG blends with lower
flavor concentrations as the flavor gets to harsh when vaped at extreme high end conditions. Of
these a extremely small fraction "may" be using one of those juices with very high diketone counts.
Even if they all got sick (which is very highly unlikely) it would represent a statistically insignificant
percentage of the vaping population.
:2c:
Regards
Mike
 

Alien Traveler

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Two can play this game. I read the forums too. A solid 80% of vapers use regular ego type bats and
or VV/VW set ups with clearo's or cigalikes. The 20% using higher end high powered mods are mostly duo-
users. They use more standard gear along with their big set up. The small percentage of exclusive high
powered only users do not use 20 ml or more on a day to day basis. Those that do vape 20 ml or more
on a daily basis are by far a very small percentage. They tend towards high VG blends with lower
flavor concentrations as the flavor gets to harsh when vaped at extreme high end conditions. Of
these a extremely small fraction "may" be using one of those juices with very high diketone counts.
Even if they all got sick (which is very highly unlikely) it would represent a statistically insignificant
percentage of the vaping population.
:2c:
Regards
Mike
OK. I understand you. The heck with those vaping 10+ ml of buttery juices. They just ruin our day.

P.S. I am amazed with your statistical powers.
 
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VNeil

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Making popcorn, smoking, and vaping, all rather different. Coming at us in different ways. Airborn dust, smoke, vapor. Mixed or in solution with different carriers. Hot, cold, warm. Steady continuous exposure, intermittent high exposures to hot vapor or smoke with breaks in between.

I don't think we can go from a handful of cases of BO in popcorn workers to saying smoking or vaping are likely to be dangerous. Neither can we go the other way and say that because smoking DK's hasn't led to large outbreaks of BO that vaping the stuff is safe. Or that because supposed cases in popcorn workers appeared within a couple of years that five years of BO-free vaping proves there's no danger. The only bit of what I see as reliable evidence is that rats or in-vitro tissue exposed to very high levels of the stuff show consequences. But there's a big gap between that and vaping in the real world.

We have very little information. I see no justification for confidently believing that vaping DK's is either safe or not safe. That's not going to matter to unprincipled people who are looking for ammunition to shut vaping down. But it should matter to us.

A lot of these threads seem to be based on "proving" by debate and analogies and reductio arguments and so forth that it is either safe or not safe. We all have to make decisions based on our best judgement, or best guess.

You said:

The only bit of what I see as reliable evidence is that rats or in-vitro tissue exposed to very high levels of the stuff show consequences.

Do you really believe that lab rats are more reliable evidence than ONE BILLION SMOKERS? And millions of vapers, who have been vaping for 7 years or more? Do you believe that lab rats and concocted short term tests of tissue samples trump the experience of ONE BILLION SMOKERS??????

Lab rats and tissue experiments are considered less than ideal proxies for the real world. Those experiments are generally done with the absence of large scale epidemiological evidence. They are considered a less than ideal proxy, a less than ideal model, of the real world. They are useful to suggest, and only suggest, what might come from a large scale, long term, epidemiological study.

But in this case, we have the real world epidemiological evidence of ONE BILLION SMOKERS, fully one seventh of the world's population, that contradicts that "less than ideal science". Not ONE SINGLE CASE of BO has ever been found in a smoker (outside of popcorn factory workers and the like).

The real science here is sociological, the science of propaganda and how propaganda can be used to convince people that plain simple evidence should be ignored. And how it is so, so effective.

But don't confuse science with propaganda. Science is the business of applying observations in order to prove or disprove theories. Here the observational evidence is as clear as it possibly could be.

If you wanted to try to determine the long term impact of inhaling some random substance (such as the other hundreds of flavors we vape), but there were no large scale epidemiological studies available, then lab rat experiments are the next best thing. But that next best thing is far removed from real world observations of human populations.

Why people such as yourself choose to ignore or belittle the REAL SCIENCE of ACTUAL OBSERVATIONS OF THE EFFECTS ON HUMANS is beyond my comprehension, but a very good study of the art of propaganda. If you truly believe that lab rat experiments trump the overwhelming conclusion based on ONE BILLION human test subjects, you need to look deep into yourself and your beliefs, and try to separate "science" from propaganda.

I'm not picking on you. Your views represent the crux of this argument, and the fallacy of the propaganda. In fact, the medical community was in total agreement that BO is a DUST BORNE hazard, until politics entered the "science". And then we were back to hunting for witches, which is where politics always takes science when science is willing to go there. We've learned nothing in the past 400 years. We are still burning witches at the stake, regardless of the overwhelming evidence to the contrary.
 
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englishmick

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In current reality, we are set up to argue (for / against) the idea that vaping diketones is potentially dangerous unless proven otherwise. How is that not applicable to every other ingredient/compound in vaping? And then how is that not applicable to every aspect of life?

The only difference between diketones and, say, butyric acid or glycerol is some rather weak hints, with (added in response to vneil) much more significant evidence to the contrary. Popcorn workers, rats, and petri dishes. And though that's weak in terms of evidence, it is a difference, and it isn't zero. Something versus nothing is a difference.

Personally I think the chance that vaping diketones is dangerous based on what's on the table so far is very small. I certainly don't think we are anywhere close to a place where any of these chemicals should be banned. Other than in the State of California I guess.

But everyone has the right to make decisions for themselves. We do it every day on limited evidence. And for that matter everyone has the right to actively campaign for the position that there is definite danger, or that there is zero reason for concern, or anything in between. That debate has the value that people who haven't made up their minds are exposed to different opinions.

My own choice is that I avoid diketones as far as possible, and vape unflavored with a few drops of my home made juice added to the tank, in case there are other flavor chemicals that could cause me harm. I have no idea whether this will turn out to have been a wise decision, but it's mine to make. I'm not going to bash anyone else for making different choices or try to persuade other people to follow me.
 

VNeil

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OK. I understand you. The heck with those vaping 10+ ml of buttery juices. They just ruin our day.

P.S. I am amazed with your statistical powers.
Where is your statistical evidence that 10+ mils per day is the norm for the 9 million USA vapors, aside from the rest of the world?
 

Alien Traveler

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Where is your statistical evidence that 10+ mils per day is the norm for the 9 million USA vapors, aside from the rest of the world?
So, we are not discussing the fact that a vaper can consume as much diacetyl as a smoker anymore. Good.
We are now talking about whether we should pay attention on minority of vapers (5-20%, I guess) who vape a lot... Whether they worth of our attention... I am sorry, I am not interested in such discussion.
 
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