Harvard Eliquid Study Today

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Robino1

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Dr. F's response to this:

A new study finds diacetyl in e-cigarettes but exaggerates risks and fails to discuss about smoking

Although I agree that we should know if e-liquids contain diacetyl and acetyl propionyl, I must note that the study has missed some very important points. One is the assessment of the levels found in their samples. The levels presented in Figure 2 are quite low, much lower that what we found in our study. In many cases, levels of these compounds are absolutely minimal, and it is NOT expected to raise any concerns about human health effects. Additionaly, the authors FAILED to mention the presence of these compounds in tobacco cigarette smoke. This omission creates the impression that e-cigarettes are exposing users to a new chemical hazard, while in reality their exposure will be much lower compared to smoking.
 

Douggro

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alien Traveler" data-source="post: 17030733" class="bbCodeBlock bbCodeBlock--expandable bbCodeBlock--quote js-expandWatch">
alien Traveler said:
This study is based on fact. Do not dismiss facts.
It is interpretation that is questionable.
I don't want to be dismissive about the presence of compounds like diacetyl in our juice because there is an associated risk with it. We, as vapers, should not be blind to the reality of what we are ingesting and the risks it may carry. But as I noted earlier, there is nothing that I saw in the study paper that established what the OSHA / NIOSH acceptable level of exposure is. So their findings are supported by the data but there's no qualification of whether that data supports their hypothesis that e-liquids contain dangerous levels of diacetyl and other compunds.

I say it again: Figures don't lie, but liars sure do figure.
 
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Alien Traveler

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I don't want to be dismissive about the presence of compounds like diacetyl in our juice because there is an associated risk with it. We, as vapers, should not be blind to the reality of what we are ingesting and the risks it may carry. But as I noted earlier, there is nothing that I saw in the study paper that established what the OSHA / NIOSH acceptable level of exposure is. So their findings are supported by the data but there's no qualification of whether that data supports their hypothesis that e-liquids contain dangerous levels of diacetyl and other compunds.

I say it again: Figures don't lie, but liars sure do figure.
Yes, nothing in the study, but as I have learned in another thread, it looks like 20 mkg/ml somehow corresponds to OSHA safety limit:
study : Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione......
 

DeAnna2112

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I think it is important to compare risk to vaping verse smoking, however, any health concerns related to vaping is not then simply dismissed or irrelevant just because it is a lower risk. My priority is to reduce all possible risk that are associated with vaping when that is an option. Smoking is behind me..i am focused on vaping and it's risk.. not smoking risk or it's comparison to vaping. I would think anyone contemplating quitting smoking would want to do so in the safest way as well because by the time they are looking to vaping, they are looking for a healthier alternative..not a new way to destroy their lungs...or they would at least like to be aware of risk they can avoid so they can decide for themselves. I think these articles help with that awareness.

Many eliquids have different levels of diketones in them and the million dollar question is...at what level should we be concerned. For me it's a matter of accepting they don't know so it becomes a matter of do i vape liquids with diketones, at any level, or not. Dr. F says they don't belong in there and we should avoid them. My hope for others is that all vapers are aware of these potential risk as well and have purposely chosen to vape diketones if they do...unfortunately though, many are not even aware of the concerns these chemicals have raised. Again, these articles help raise awareness and let people know they have an option to avoid diketones altogether by informing them of what liquids have them and that one can vape without them in it.
 
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Douggro

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Yes, nothing in the study, but as I have learned in another thread, it looks like 20 mkg/ml somehow corresponds to OSHA safety limit: study : Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione......
The more I read this thing, the better it gets.. :-x
"A convenience sample of 51 e-cigarette flavors was selected for use in this study. Electronic cigarette cartridges, liquids, and their associated devices and batteries were purchased online and in retail locations. We evaluated 51 flavors, including all available flavors from three large cigarette companies (Brands A, B, and C, with 2, 2, and 7 flavors, respectively); 5 flavors from a large independent e-cigarette company (Brand D); and 24 additional flavors from three e-cigarette distributors (Brands E, F, and G, 10, 8, and 6 flavors, respectively) that we selected based on their potential appeal to children, teenagers and young adults (Table 2). In addition, we evaluated 11 e-liquid flavors that are inserted into a cartomizer (disposable cartridge and atomizer system) (Brands H and I, 6 and 5 flavors, respectively)."​
Would it be fair to infer that they solely tested e-cigs/cigalikes from this statement?
And just how did they determine the "potential appeal to children, teenagers and young adults"?
o_O
 
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Alien Traveler

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I think it is important to compare risk to vaping verse smoking, however, any health concerns related to vaping is not then simply dismissed or irrelevant just because it is a lower risk. My priority is to reduce all possible risk that are associated with vaping when that is an option. Smoking is behind me..i am focused on vaping and it's risk.. not smoking risk or it's comparison to vaping. I would think anyone contemplating quitting smoking would want to do so in the safest way as well because by the time they are looking to vaping, they are looking for a healthier alternative..not a new way to destroy their lungs...or they would at least like to be aware of risk they can avoid so they can decide for themselves. I think these articles help with that awareness.

Many eliquids have different levels of diketones in them and the million dollar question is...at what level should we be concerned. For me it's a matter of accepting they don't know so it becomes a matter of do i vape liquids with diketones, at any level, or not. Dr. F says they don't belong in there and we should avoid them. My hope for others is that all vapers are aware of these potential risk as well and have purposely chosen to vape diketones if they do...unfortunately though, many are not even aware of the concerns these chemicals have raised. Again, these articles help raise awareness and let people know they have an option to avoid diketones altogether by informing them of what liquids have them and that one can vape without them in it.
Risks are unknown. May be exaggerated.
But it looks like quite a few juices on the market exceed safety limit for industry workers.
 

ENAUD

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I think it is important to compare risk to vaping verse smoking, however, any health concerns related to vaping is not then simply dismissed or irrelevant just because it is a lower risk. My priority is to reduce all possible risk that are associated with vaping when that is an option. Smoking is behind me..i am focused on vaping and it's risk.. not smoking risk or it's comparison to vaping. I would think anyone contemplating quitting smoking would want to do so in the safest way as well because by the time they are looking to vaping, they are looking for a healthier alternative..not a new way to destroy their lungs...or they would at least like to be aware of risk they can avoid so they can decide for themselves. I think these articles help with that awareness.

Many eliquids have different levels of diketones in them and the million dollar question is...at what level should we be concerned. For me it's a matter of accepting they don't know so it becomes a matter of do i vape liquids with diketones, at any level, or not. Dr. F says they don't belong in there and we should avoid them. My hope for others is that all vapers are aware of these potential risk as well and have purposely chosen to vape diketones if they do...unfortunately though, many are not even aware of the concerns these chemicals have raised. Again, these articles help raise awareness and let people know they have an option to avoid diketones altogether by informing them of what liquids have them and that one can vape without them in it.
Good points, and to add, there are more and more never smokers taking up vaping as its popularity increases, I'm all for studies and tests because if vaping is going to be here to stay, identifying and determining potential harm factors will only make it safer for all.
 
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DeAnna2112

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The more I read this thing, the better it gets.. :-x
"A convenience sample of 51 e-cigarette flavors was selected for use in this study. Electronic cigarette cartridges, liquids, and their associated devices and batteries were purchased online and in retail locations. We evaluated 51 flavors, including all available flavors from three large cigarette companies (Brands A, B, and C, with 2, 2, and 7 flavors, respectively); 5 flavors from a large independent e-cigarette company (Brand D); and 24 additional flavors from three e-cigarette distributors (Brands E, F, and G, 10, 8, and 6 flavors, respectively) that we selected based on their potential appeal to children, teenagers and young adults (Table 2). In addition, we evaluated 11 e-liquid flavors that are inserted into a cartomizer (disposable cartridge and atomizer system) (Brands H and I, 6 and 5 flavors, respectively)."​
Would it be fair to infer that they solely tested e-cigs/cigalikes from this statement?
And just how did they determine the "potential appeal to children, teenagers and young adults"?
o_O

Just my two cents and interpretation.....i didn't see anything wrong or sketchy here and they were upfront about their focus group.
 

Douggro

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Just my two cents and interpretation.....i didn't see anything wrong or sketchy here and they were upfront about their focus group.
I get your point and it's valid. But selecting flavors that they think are appealing to those groups can induce a statistical differentiation over presenting a list of flavors to a defined number of subjects from each group and using those selections for the study. That's flawed methodology in my book: the researchers are inserting their biases into the sample.
 

Topwater Elvis

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The folks the FDA listen(s) to have repetitively stated there are no exposure level standards that are relevant or applicable to flavorings as they are used in e cigs/vaping. None.

---> https://www.femaflavor.org/safety-assessment-and-regulatory-authority-use-flavors-focus-e-cigarettes


(In earlier reports), Fema also identified & reported to the FDA 1037 chemicals used to produce flavorings that have at least the potential to cause respiratory harm.
Over 300 were considered high risk at any exposure level, more than 40 were considered unsafe to inhale in any amount.

The few chemicals some vapors are concerned with (the ones you hear the most about) were not listed in the high risk or unsafe at any level categories.

Just because your liquid supposedly doesn't contain whatever your worried about doesn't mean it doesn't contain something worse that we haven't focused on or tested for.

Considering one simple single flavoring concentrate can contain as few as 3 to as many as dozens of these chemicals, then these single flavorings are combined with 1 to dozens of other flavoring concentrates to produce an eliquid flavor, the chance of having at least one of the 340 plus high risk chemicals floating around in your eliquids seems quite possible.

Doesn't bother me at all.
Safer than smoking, IMO yes.
I'll take my chances with the 340 or so instead of the thousands known in cigarette smoke.
 
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beckdg

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I don't see these articles as a bad thing, i just see it as a means to make people more aware of the concerns and potential for harm so they can make a more informed choice as to whether they wish to vape flavors or not. Flavoring is optional and not necessary to vape, so folks that vape who may be concerned by this are more then able to do further research on the matter and make up their own minds about it. Many vapers are not even aware of these chemicals so articles like these that raises these concerns gets the word out and prompts awareness.

Bottom line...I always hope that those who are vaping juices with these chemicals in it are well aware of the concerns and potential of harm that have been raised so at least they know upfront the potential risk they may be taking.

From various researches i have read, there doesn't seem to be any question about whether or not these chemicals are harmful in the eyes of the medical community, it's a question of at what level does it become harmful especially when vaping it. We already know that vaping these chemicals reduces lung function according to Dr. F after conducting some respiratory test...so that is already established by one of our own researchers.

I say let folks make up their own minds on how they feel about the research that is out there...but let's keep awareness as the main priority so they can make an informed decision.

I think society over the many years has seen and experienced through someone they know the god awful dangers of cigs. They have seen the commercials with those used as examples of what cigs did to them....or lost someone or has watched someone they know suffer from it's consequences. I highly doubt most people believe that vaping is worse then cigs...i just find that hard to believe unless they are extremist just looking for something to oppose. Hell, we have pro vaping extremist who are just as bad....but those extremist on either side are the exception to society as a whole, not the norm.
Just my two cents....i just want vapers to be aware so they are vaping based on all the information to decide for themselves.
It's not the information that's the problem.

We've known this information here and discussed it in depth for a year or two.

Some of us are more precautious than others.

We're all enjoying the benefits of cutting down or cutting out smoking and tobacco.

But the problem is who, when, where and how this information is being displayed, used and manipulated to misdirect the public... to GIVE THEM THEIR OPINION and LET them think it's their own.

The masses are sheeple for "a good cause".

Tapatyped
 

beckdg

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Risks are unknown. May be exaggerated.
But it looks like quite a few juices on the market exceed safety limit for industry workers.

Industry workers can't take a breath between puffs and aren't diluting the concentration with clean air on every breath.

Those numbers are completely unrelated and useless.

The only thing they're good for are as indicators that we need to figure out if and when these chemicals become cause for concern how we use them.

Tapatyped
 

Alien Traveler

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Industry workers can't take a breath between puffs and aren't diluting the concentration with clean air on every breath.

Those numbers are completely unrelated and useless.
You may want to talk about it with Dr. F. It's his interpretation, based, I believe, on total daily consumption of chemical (which looks as right thing to do).
 

WharfRat1976

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The vape community people are like tiny little ants on a sand hill, scurrying about being very busy performing all their little necessary and self important functions as Big Tobacco walks by with a size 14 and a half shoe and just steps on it like another bug.
 

WharfRat1976

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The vape community people are like tiny little ants on a sand hill, scurrying about being very busy performing all their little necessary and self important functions as Big Tobacco walks by with a size 14 and a half shoe and just steps on it like another bug.
Could Dr. FARCE A LEENOS name be any more ironic?
 
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