I started on 24 mg with a blu e-cig. I go back and forth between 3 and 6 in my Subvod, but I tend to go through about 5 or 6 ml in day doing that. My soon to be ex wife, who never smoked, started vaping with a Kanger esmart but she uses 0 nic. I tried it, and it just didn't cut it for me. But unless you're a pregnant or nursing mother, nicotine isn't really all that harmful. So the best suggestion I could give would be go with what's working for you, as long as you stay off the analogs.