A few thoughts...
I agree w/Katya and Groundhog. I'd already perused acres of the main forum before I hit this one, and then read piles in here, but few have my rabid curiosity and patience. I am a RTFM girl and then some. New buyers aren't necessarily going to ever do internet research to any extent. Can this forum be linked on the site?
Anyway, I think it should be ordered into very clear, succinct little sections that correspond to the first two levels of experience and interest and emphasize ease of use.
A brand new noob wants to know how to use each piece of equipment (tho it's all very intuitive), determine the right nicotine level, be told how how to inhale properly, how to tell when carts are dry, about what they equal compared to a pack of cigarettes or some guide, even @222 hits or whatever it is (so as to know how much to order/carry to work, and what they're paying for compared to cigs), how best to store carts (dark, cool, if that's true - seems some variance on that one), the relative merits of different lengths and of man/auto/PT, and of regular/premium carts (including the felicitous, scary-to-noobs crackle-pop), the diff between pg and vg, battery maintenance (PCC here), stuff like that. Photos are always nice. Samplers should be highly recommended and a note that taste prefs can be surprising. (And there should DEFINITELY be a good selection of premium samplers available.) I'm sure there's more - think back to week one. (I'm just throwing stuff in, it should be ordered according to likely sequence of need.) All of this can actually be very succinct; only in here do we obsess and obsess on the finer details of every aspect.
Next section would be all about using juice - whether or not to top/refill at all. Some don't, remember. I initially figured carts were just disposable and that's a place where some would rather stop. So, reusing cartos vs buying blanks would go here. So would topping to keep one cart going, and for how long that's possible.
(People keep evolving - at one month I've boiled, syringed, rinsed and etc., and then quit that - I just top and top until things seem exhausted, or use blanks for a new flavor, and finally throw 'em away. Enough is enough, for now.)
Leaford's excellent video (second half redo, with no hesitation re how much juice is needed, hee) is the best how-to intro to that that I can think of, with a note that other methods are possible.
Then maybe a trouble shooting section. I never trust a manual with no trouble shooting section.
A bad batt/PT at the start could really discourage tentative folks. What indicates faulty equipment/carts, and what is something that's user error or can be easily remedied? Warrenty brag here. I've had so few problems with equipment that I dunno, but a scan of the forum should indicate the most common difficulties.
I think that the thing should begin with the sweet truth - these are plug and play ecigs. I opened mine in the car after ripping package open at the first red light, assembled one at the next red light, rejoiced to note that it was already charged, and was vaping away joyfully the rest of the way in. With all due respect to PC folks, and without opening that ridiculous ancient debate, please! - it's a Mac thing, market-wise. Elegant, easy, nice on the eye, and top quality.
(I got my first MAc when they were a very, very young company. I could call them at 2 AM with the stupidest damned question, get an immediate answer and unbelievably patient, friendly and skilled tech support, for free. That went on for years. Lotta cool freebies, too, back then. And the same sort of insanely enthusiastic product loyalty. In some ways, especially if ecigs are gonna go all huge and horrible, V4L is already in Mac mode and might use that as a good start-up model.)
I think that success stories are verboten, as health claims or advertising openly as a cessation device are problematic because of all the damned FDA stuff. "Alternative" is now the suggested approach, I believe. One company gets bashed for making it look like too much fun, another for making it seem medically efficacious.
It will all come out in the warsh, as mama always said.