In the beginning of vaping, I thought I had an allergy to PG. I think it was just my body going "good grief, the 4000 chemicals in the cigarettes isn't enough so lets add some more." Come to find out like a lot of B and M's they were selling cheap Chinese juice relabeled as there own brand. So I started making my on and I used baby water in the grocery store. Its as clean as water can get and I mixed it in with my Non GMO organic VG. The mixes came out nice. They were simple flavors but served the purpose. I've since realized I can handle PG ok and ordered a small bottle of it for mix high vg mixes but wanted to try something else to thin it with. It was explained to me that the flavor is carried by the PG and the clouds from the VG. I cant say I noticed any real difference which means one less thing to buy. If your doing elaborate mixes with 3 or 4 flavorings at a time then PG may be better