Hi son et luminiere,
I am very sorry to hear of the diagnosis for your family member. I am NOT a doctor, but I have personally read a lot of material on that subject due to a similar personal situation. Please take the below from a fellow interested (and affected) lay person.
The study that jplanet references is from 2003 and was conducted only on rats. As far as I know, it was never moved forward to a human setting.
As far as I can tell, nicotine can cause damage in two ways:
1) It is considered a "vasoconstrictor" - generally, it can cause blood vessels to contract thus making the heart work harder. Over an extended period of time this could potentially lead to heart damage.
2) It can cause "endolethial damage" - generally, nicotine MAY cause damage to the lining of blood vessels - which then could cause cholesterol build up, and thus could cause vessel inflammation. They are not 100% sure - this assumption is due to an elevated protein found in some nicotine users and those users have other items ingested as well.
My personal opinion is yes, as a stimulant like any other, nicotine can cause heart damage.
HOWEVER, there are several more educated people than me in the medical field that disagree. Carol Southard, a health professional, RN, MSN and Smoking cessation consultant said in 2008:
"Nicotine is not the dangerous chemical in cigarettes. Cigarette smoke contains many harmful chemicals, and it is these, not nicotine, that are responsible for the heart attacks, cancer, and lung disease. The risks of cigarette smoking are much greater than the risks of NRT [nicotine replacement therapy]. NRT packages come with many warnings and directions that can lead a person to believe that NRT is far more risky than it actually is. It is a mistake to think that any NRT product is as dangerous as cigarettes." [emphasis added]
Caffeine (and several other stimulants we find in every day life) have similar effects physiologically as nicotine. Without abstaining from these as well it is difficult to point to nicotine as the culprit.
However, the carbon monoxide, nitrogen oxides, hydrogen cyanide and ammonia in regular smoking (along with hundreds of other extremely dangerous substances) have been proven to cause heart disease (and cancer) in and by themselves. Excessive alcohol abuse is also terribly hard on the body and most especially the heart and liver.
Alcohol abuse and smoking are #1 and #2 for heart disease. Follow that with age, stress, heredity, hypertension, caffeine, etc... nicotine is personally the least of my worries.
Son et luminiere, you will definitely be in my prayers. I lost my father to alcohol abuse and more recently a very dear friend to cancer caused by many years of smoking. I wish there were something I could write to alleviate some of your pain. I hope this provides some information at least to guide you on your search.