I really have no idea, but have read many threads about types of alcohol that are not good to vape, diacetyl etc. I just don't think I'd trust it myself. But I tend to be on the more leary side of this. I'm not sure about the actual safety of any of this, but it certainly seems better than smoking. Since that is 1/4 alcohol, and you need to use more of it, I myself wouldn't do it.