Nic absorbtion through the skin

[Surf Monkey]

You can say practically the EXACT same things about caffeine.

 

[Kate51]

You misunderstand me, as I like the effect. I'm only worried that our nanny-state overloards will have another reason to ban liquid nicotine if anyone can just rub in on their skin to get really high. That's why I mentioned free-base nicotine in my original post. I have read that if you could free-base nicotine it would have an extreme psychoactive effect (different than smoking). I'm wondering if rubbing it in a place where the veins are close to the surface of the skin (as I did) has a qualitatively different effect like free-basing, or if what I felt was simply due to absorbing more total nicotine.

Is the effect and toxicity of nicotine simply function of the total amount absorbed by the body, or is there a distinction between the amount we absorb and the amount we get into our bloodstream? That is, maybe you could get a more psychoactive effect by getting more into your bloodstream without increasing the total amount of nicotine to toxic levels.

So, perhaps I can refine my orignal question. Is a single drop of liquid more toxic if absorbed in some other way than if it were vaporized?

In a word? YES

 

[dave8944]

I appreciate all the replies. I do wish there was a search function for the forums to better review archieved posts.

I realize eating tobacco will release more nicotine into your system than smoking the same amount of tobacco. That's why I say x-quantity of nicotine, let's say the 1.1mg you might get from smoking a cigarette. If you take that same amount of nicotine and absorb it more directly into the system through the skin, would it have the same toxicity or more? I think it must be the same, but the effect is profoundly different. It may be likely that such fast uptake of nicotine will change the toxicity equation (0.5-1.0 mg/kg or 55-65mg per day for an average person). I don't know, but all the information on the internet quotes the same sources and doesn't mention a difference. There is mention that nicotine is more toxic than other alkaloids (such as .......), but again, is that at the quoted levels. If so, then I worry about abuse of the liquid. That would leave a fairly large window where a high could be obtained without toxicity. Perhaps the window between high and dead is smaller with nicotine, making it more dangerous for such purposes. I wonder what the truth (not hype) might be.

Please understand I have a serious addiction to nicotine! I was on nicotine gum when it first came out and required a doctors prescription, so it's been a long time. I love patching too. It was the only thing that kept me from waking up to smoke every night and made air travel possible. Absorbing liquid nicotine is nothing like getting it from a time released patch.

I'm surprised at the horror some have that others might want to get high, but at least be honest with yourself that your addiction to a psychoactive substance represents exactly that. We are all in the same boat. Some of us have just been waiting longer than others to get out of it.

 

[Kate51]

Dave8944 Post #23 was excellent. There for a minute I almost waited for the link to the Russian Roulette website. Glad to see you weren't going there.
Let's encourage probing minds, but not with bullets. Or free-basing nicotine. But I have to admit, I get a little nervous about the "cavalier" attitude some people have towards danger in general but especially with their own chosen indulgences. Maybe I'm just getting old, eh, Tropical Bob! It's not like 44 years of smoking lends itself to being intelligent.
Too soon too old, and too late smart

 

[sMuCk_fOg]

From the information out there I can only figure there is about 1 cig's worth of nicotine per drop of liquid (I'm using 24mg liquid)

If that's true... man am I going through some
hEaVy nIcOtInE.
However,I'm still pretty convinced that all of this stuff coming from china is zero nicotine content.

I drip 4 drops of 36mg juice on my atty ,and get about 5 long deep drags - repeat about 100 times a day.
I feel nOtHiNg!

I take a drag off a Marlboro lite,
I almost fall down from the rush.

 

[808kicks901hits]

If that's true... man am I going through some
hEaVy nIcOtInE.
However,I'm still pretty convinced that all of this stuff coming from china is zero nicotine content.

I drip 4 drops of 36mg juice on my atty ,and get about 5 long deep drags - repeat about 100 times a day.
I feel nOtHiNg!

I take a drag off a Marlboro lite,
I almost fall down from the rush.

I've read that the body absorbs nicotine differently from vaping (1/10 the amount or effect). But it's fact that the cigarette companies put chemicals in cigarettes which amplify the effects of the nicotine. I'd tried a lot of different smokes in the time that I still smoked. Marlboro's are the best. Also have heard they have the most chemicals.

 

[sMuCk_fOg]

I've read that the body absorbs nicotine differently from vaping (1/10 the amount or effect). But it's fact that the cigarette companies put chemicals in cigarettes which amplify the effects of the nicotine. I'd tried a lot of different smokes in the time that I still smoked. Marlboro's are the best. Also have heard they have the most chemicals.

That's kinda my point...I think that as long as we can get that Deeeep dowwwwn lung filling hit ,
the nicotine content of yer juice is meaningless ,
ergo the absolute necessity of a MANUAL switched Personal vaporizer.

 

[nibb]

I spilled some 24 mg juice on my finders and did not felt anything, never. I suppose some people absorb is faster then others. But I do feel it when vaping.
Anyway, spilling the juice on your fingers on purpose would be just like eating cigarrettes.

 

[dave8944]

There is definately nicotine in the juice! I don't feel it absorbing it through my fingers either, but I'm convinced the bit you get on your hands when refilling is where most of the nicotine is coming from while vaping. The bit I absorbed through my skin near my artery resulted in an effect I would liken to the rush one gets using intraveneous drugs. That's what made me worry about what others might do. It's not the same as getting too much nicotine from smoking, or the head rush you get when smoking a cigarette after a long period of time without one.

I finally spoke to a chemist in my family about the issue. He says there likely is a lower threshold for toxicity getting it all at once versus the how much you can absorb for a whole day. However, when I look up "accute toxicity" all I get is the same previously quoted figure. We'll definately be finding out once the masses start using it as some idiots will defninately be overdosing on the stuff. On the brighter side, the chemist was somewhat interested in producing synthetic nicotine if the FDA were to ban the use of liquid nicotine derived from tobacco.

 

[Kate51]

A known neurotoxin, nicotine is also one of the most highly addictive substances available for public consumption. More lethal than strychnine, just 60 milligrams of nicotine on the tongue —about three drops—is enough to kill a 160 pound person. In contrast: The lethal dose for strychnine is 75 mg, for diamondback rattlesnake venom it’s 100 mg, you’d need to ingest 200 mg of arsenic to do somebody in, and Cyanide's lethal dose is 500 mg.

Here's an interesting by-the-way!