Basically, the answer here is that your build doesn't matter, the wattage does.
So this is oversimplification, but basically what these boxes do to get the higher voltage is pull extra amps from the battery and convert it. The wattage stays the same
throughout the circuit. Since we know the battery's feeding 4.2v on a full charge and we know the wattage, we can figure out the amp draw from there. Your coil resistance doesn't touch anything on the battery side, so it doesn't make a difference to battery life in a variable
mod.
Let's talk through the numbers on your two buids.
.5ohm-3.8v-7.7amp=30watts or 1.2ohm-6v-5amp =30 watts
Your atomizer is seeing 3.8 volts and 7.6 amps at 28.88 watts in this first build. On the other side of the chip, to get that 28.88 watts with a 4.2v input, the battery's putting out 6.88 amps. In the real world, you lose a little bit to the chip, so it's really closer to 7.94 amps at 33.33 watts, figuring your mod has 90% efficiency. On a fresh 2500mah battery, that gives you about 17 minutes of vape time or 208 five second pulls.
For your second build, the numbers work out to 30 watts at the atomizer, so (again assuming 90% efficiency), you're getting 7.94 amps at 33.33 watts going into the chip. Battery life is essentially the same, with 17 minutes or 200 five second pulls.
If you swich it to a 15 watt setting, you're only pulling 3.97 amps from the battery, with a 33 minute/400 pull vape time, so half the watts = double the battery. Doubling the watts to 60 gives you 8 minutes/100 draws, so double the watts = half the battery. Make sense?
Steam engine has a
battery life calculator you can use to run the numbers. Play with it a little and see what you find.