It should ask if there's a new coil. Then apply new settings.
I'm using a subtank mini on the istick and it's working very well. Started out with Kanthal A1, then NiCr wire, moved on to Ti, then SS316L, now back to Kanthal. Tc, VW, Twisted, claptoned, you name it and the stm will take it. Very easy to build on.
I've only tried a few tanks mentioned in this thread, so you'll get my subjective opinions on them. I've sold or given away most of them, now using only the subtank mini and wotofo serpent. This is my list of what i tried, not chronologically but best to less good:
1 Wotofo Serpent - great taste, great airflow
2 Subtank Mini - supereasy to build
3 OBS Crius - cracked the insulator when adjusting center pin, easy to build coils
4 Griffin - weird ring that holds the cotton
5 Lemo 2 - nice topfill
6 Goblin v1 - small, unhandy screw for filling, get the v2
7 Taifun GT-T v2 - easy to build, lots of taste
8 Kayfun Lite Plus v2 - decent mtl tank with good taste
9 Orchid v4 - tastefull dual coil, needs a lot of power
10 Uwell Crown - airy semi-mtl tank, easy to build
Maybe start out with a stm and a serpent, then later add some dual coil monsters to it. I'm a single coil dlh tank vaper, i'm sure there are many mtl quad coil dripper vapers out here who can help you with their experience.