I would be less concerned with how it is made and more concerned with its history of being safely used as an inhalant. PG vapor is used in hospitals to delivered inhaled medications, even for lung transplant patients. It's also used in concert fog. And it has been used in asthma inhalers and nebulizers since the 1950's.
PG is thin and lets through the most flavor and nicotine hit, as well as the most nicotine irritation. VG is thick (too thick to work alone in many popular methods of vaping), dulls everything PG lets through and adds thicker visible vapor. Most people use blends. I use high-PG blends like 80PG/20VG in cartomizers.