Hhhmmm... there's no reason why it wouldn't work. There's little difference in the various distilled alcohols aside from where they get their sugars; they are all ethanol. Whiskeys are distilled from grains and starches-- a/k/a "beer"-- (yes, including vodkas) that must be soaked in water to release the sugar. Brandies are distilled from fruits juicy enough to be pressed and have the sugars run out in the juices-- a/k/a "wine". The rest is just flavoring, and can come from the original distillate (most brandies have a strong fruit flavor), or the aging process (that's why they charcoal the inside of the aging barrels for Bourbon), the smoke from the fire used to heat it (Scots) or by other processes. Gin, for example, is a flavored vodka, and it takes its distinct flavor from having the distillate steam pass through a chamber filled with various flavorful organics-- generically the "aromatics"-- always including juniper berries and usually other things like citrus peels and the like, before it is condensed into liquid. I had an odd bottle of Scots once which was aged in a barrel previously used to age a sweet porter; interesting flavor, actually, the peat was almost drowned out. So there are any number of methods.
But with all that said, I am still not certain how good an idea it is. In general, in vape juice alcohol is generally added, usually in tiny quantities, to increase throat hit. The normal quantities are too small to impart much flavor; by the time you get enough in it to taste it I suspect you'll need a stainless throat lining to vape it without screaming. I think you may do better pursuing the flavors by using flavoring molecules available from various vendors intended to mimic various spirits or even mixed drinks.
If there's some off-the-wall brand of whiskey you just have to have, and it isn't normally matched in commercial flavor profiles, you might make your own by freezing the water out of it. If you take a small bowl of spirits and put it in the freezer and let it get cold, it won't freeze because of the alcohol. But if you then float a few chips of water ice in it the water used in proofing (diluting the pure spirit) will freeze out of the mixture by adhering to the ice. This is normally done by evil-minded people who wish to unexpectedly increase the potency of a drink without changing the flavor much, and the "improved" spirits are poured and the ice is discarded. But if you saved the ice, and melted it, I would not be shocked to find some of the flavor molecules went along with the water. Perhaps that might be added to your mixture. Might be worth a try, anyway.