So I pretty much love it....no burnt hits when I forget to squonk...no leaks. The oring on the 510 seals well, nothing gets out. Bottle is about the same size as my Reo Grand bottle. I can operate left or right handed and the bottle is fully accessible. Right hand? squonk with thumb, fire with fore finger (although the curve is in the wrong direction ergonomically) Left hand ( this is what I do most of the time) squonk with fore, middle or ring finger...fire with thumb.
No glitches...no problems. Although I may look at a different topper since the real estate for 2.5 ID coils is a little sparse with the Cyclone.
If I were to be nit picky, attaching the tube to the 510 metal tube can be tricky because it is dark in there. But all of the advantages outweigh a minor inconvenience IMO. Once you have done it a few times, you don't need to look because you can feel the tension when you press the bottle in.
And now I am giggling at myself because I can still get the ergonomics in the right hand if I flip it...hahaha...oops