I use them all the time with my Big Chuck, they are Big Chuck friendly!
You just have to make sure to keep the carto wet. I get about 20 good decent puffs before I refill the carto. Probably could take a couple more puffs, but so far, I just get about 20 good puffs, put the caps back on an grab another carto.
I've yet to "fry" a carto!
It only takes a couple seconds on the button to get a TH & good vapor output!