There seems to be a lot of confusion in this thread vs 100mg nic, 1000mg nic,
vaping vs getting on your skin, etc.
1000mg nic (pure nic) is not widely available and is super dangerous. There are definitely juice vendors who work with it regularly without all the necessary safety equipement - but it's not something you want to mess with because the cost of an error is potentially your death. I read a post somewhere by a juice vendor who had 500mg nic in his fridge and accidentally drank some while sleep walking . .a crazy story if you believe it . .according to him he ended up in the hospital for over a week.
100mg nic is only 10% nicotine and 90% PG or VG. It is not as dangerous to work with. Nobody should ever advise you not to wear gloves - but plenty of people handle it without gloves. If you spill some on your hands - go wash it off right away . .you don't have to freak out and run for the sink . .but don't just wipe it off with paper towel.
Even 18mg nic will burn the crap out of your eyes if you get it in there . .do not let that happen under any circumstances!
40-60mg nic is enough to potentially kill somebody . .but that's the amount that would have to be absorbed. You don't get perfect absorbtion through vaping and definitely not through skin contact.
Nic is dangerous and caution is warranted .. but no reason to freak out unnecessarily.