Just make sure they are completely filled. If you want to pre-fill a punched carto before tanking it you can cut the top off of a carto condom and slide it down to cover the holes. I use a plug from an old 510 carto to plug the bottom connector and hold it in place with a napkin or tissue. Then drip or inject liquid down the sides and give it a few thermometer shakes to make sure liquid gets to the bottom. Repeat if necessary until it won't hold any more liquid and let it sit for a few minutes.