I don't know how high you are planning to go, but make sure your mod supports the resistance by checking the manufacturer's specs (some mods
do limit the higher ohms you build, although they're usually "pretty high" for an above 1.0 ohm build.
You want to make sure that you're using a wire material that doesn't require a huge amount of wattage to heat it up, if you are going over 1.0, also, as otherwise that will sort of defeat the purpose of having a cool build. You might play around with steam-engine.org, including the "heat flux" part I believe it is, so you can build something tailored to what you want.
As long as your build is solid, well the basic safely principles remain the same, it's just that you will be using lower wattage than on a sub0hm build (if you are doing it right) but that's not really a safety concern, it just likely will result in far better battery life.
Any sort of "ballpark" area where you want to build to? And the tank? Because as far as draw, airflow and etc., having that right may increase the "success" of your build. If you can't get the airflow tight enough and the draw right, it can sometimes result in a less than ideal experience. Although, there are plenty of sub0hm capable RTAs or RBAs where you can probably get things pretty "close" to a MTL draw if that's what you are looking for. etc.
Best of luck, I hope any of the above was helpful....
Anna