yeh youcan, but the problem is that the glycerin gives me rumbly stomach, gas, that's why I have to cutit as much as possible- just gotta find hte right amounts- I had thought though that straight PG was what made the vapor, but I'm not finding that to be the case- it needs the glycerin. Ruyan's cartridges come with 4 different recipes- and I was looking at them and they all contained liek 80-90% PG with only like 4% Glycerin, but I can get it to work with htose amounts for some reason- I've got 50% Glycerin 50% PG which I use for hte juice, which I use 80% of the 50/50 PG Glycerin, and the rest just tobacco juice, that is producing really good vapor so far, but is still giving me stomach rumbling/gas- straight PG doesn't cause that for me- I just gotta play with hte mix of PG/Glycerin to see how low I can go with hte Glycerin & still get good vapor.