Oh yeah mix away. That is how I started before I switched to DIY... If you have tobacco flavors - they mix well with cherry, cappuccino, brandy, etc. Coffee flavors also mix well with these flavors. You only need a small amount - an accent because the cherry and brandy flavors will over power the tobacco flavors. Think of it like cooking / baking... If it sounds like you could do that and you would like it - then you can mix it... It does take a day or two for the flavors to blend properly.