It wont suck you dry but it has an effect on your mucus membranes and skin (not unlike being in an enviroment controlled by AC all day and night) - look up PG/VG in the Library section of this forum for links to medical tests done on both. Staying hydrated jsut keeps you ahead of the humectant curve that PG and VG bring to the table - it also has other effects like improving hair and skin (extra fluids, not extra PG or VG lol). Ive vaped for 9 months and not only do I no longer have black circles under my eyes any longer I also have less facial lines. My skin is pinker too.