Personally, I've noticed I get heartburn from analogs, especially if I smoke a few too many in a day. What I've found, both in analogs and
vaping, the mucus that builds up in your mouth and throat (body's natural reaction to soothe a dry spot) eventually gets swallowed. Because it's mixed with something the stomach isn't used to, or simply doesn't like, the stomach is going to produce more acid than usual to try to digest this thick, gooey mess.
I always have a couple Tums on hand, just in case. You should also increase your intake of
water. Just drinking something might seem appropriate, but water is going to dilute stomach acids, and not cause the stomach to try to digest something. Hope that helps.