Wonderful study, the complete findings are available here.....Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices
How long till nicotine kicks in from vaping?
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Wonderful study, the complete findings are available here.....Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices
I would say it takes only seconds. The first time I tried vaping, I puffed a liquid rated at 18 mg nicotine. I got a buzz seconds after exhaling, and the buzz was more intense than what I got from smoking. In fact, the intensity of the buzz was unpleasant and I settled for a juice with only 12mg nicotine.
No matter what health professionnals are saying about nicotine being very addictive, I think that for me the ritual gestures, the inhaling and exhaling of smoke are more important than the nicotine intake.
A 30 ml bottle of juice at 12mg lasts me ten days, so I consume less nicotine than I was when smoking a pack a day, yet not once have experienced the faintest desire for an analog smoke. Vaping satisfies my taste for inhalation and exhalation better than smoking because of the flavor and because of a throat hit that is more plesant than the one from cigarette smoke. I will experiment with lower nicotine levels eventually, but I will not hesitate to go back at my current level at the first sign of a craving for an analog.
No matter what health professionnals are saying about nicotine being very addictive, I think that for me the ritual gestures, the inhaling and exhaling of smoke are more important than the nicotine intake.
A 30 ml bottle of juice at 12mg lasts me ten days, so I consume less nicotine than I was when smoking a pack a day, yet not once have experienced the faintest desire for an analog smoke. Vaping satisfies my taste for inhalation and exhalation better than smoking because of the flavor and because of a throat hit that is more plesant than the one from cigarette smoke. I will experiment with lower nicotine levels eventually, but I will not hesitate to go back at my current level at the first sign of a craving for an analog.
The researchers say that the nicotine delivery from ecigs is far slower than that from cigarettes. However, their testing and measurement methods are not always optimal, and it probably requires radioactive-tagged nicotine and cranial pickups to determine the real speed, instead of the very crude plasma nic level testing that is normally used, and which is not accurate enough for speed tests.
A cigarette smoker says they can feel the first-stage hit in 5 seconds, and the second-stage hit in 10 seconds, and basic level testing (plasma nic level) shows an effect in 10 seconds.
The 'first-stage hit' may be unrelated to nicotine and for example be a reaction to carbon monoxide.
Radio-tagged nic shows a fast effect in the brain area, around 8 seconds.
Vapers say they can feel the hit in 10 -15 seconds.
The first-stage hit comes in under 10 seconds and the second-stage is there by 15 seconds.
This is much faster than researchers say is demonstrated, but they have not use radio-tagging yet on vapers. The plasma nic level tests are too crude for reliable use in fast response tests.
Best speed test
Vapers can get a better idea of exactly how fast their gear performs by loading it with 45mg strength refill liquid, the strongest available at retail. One pull of this strength will give a far more reliable result as regards the speed measurement than a low-strength refill can. When you feel the hit from 45mg is when vaping hits for you; and when you know that time you can ignore what researchers say it is. You will feel it under 10 seconds assuming your user technique is optimal.
Usefulness of refill strength label
As several researchers have pointed out, the label strength has no relationship to the nicotine delivered to the user, on average. This is because of the large numbers of variables, some of which are:
- The label strength is sometimes inaccurate.
- Hardware has an average delivery efficiency of 50%, so only half the nic will be delivered on average.
- Since hardware efficiency varies between 10% and 80%, then if the hardware used is at the lower end of the scale, then hardly any nic will be delivered at all.
- Most tests show that there is only 10% of the nicotine in ecig vapour compared to cigarette smoke. An example of one test: vapour contained 10mcg nic per puff, cig smoke contained 103mcg per puff.
- User technique can easily halve or double the amount of nicotine delivered. It is easily possible that user A gets double the nicotine from a given set-up than user B.
- There is a difference in individual tolerance to nicotine of a factor of 10. Some people cannot over-vape 6mg strength, and some require 60mg strength to avoid relapse to smoking, and show no signs of OD at all. With this huge variation, it is obvious that what applies to one person may have no relevance to another.
- It is just about impossible, given the variation between people, hardware, refills, and user technique, that two people using the same set-up will measure the same nic plasma level; therefore label strengths are not a guide to plasma nic level.
A cigarette smoker says they can feel the first-stage hit in 5 seconds, and the second-stage hit in 10 seconds, and basic level testing (plasma nic level) shows an effect in 10 seconds.
The 'first-stage hit' may be unrelated to nicotine and for example be a reaction to carbon monoxide.
Radio-tagged nic shows a fast effect in the brain area, around 8 seconds.
Vapers say they can feel the hit in 10 -15 seconds.
The first-stage hit comes in under 10 seconds and the second-stage is there by 15 seconds.
This is much faster than researchers say is demonstrated, but they have not use radio-tagging yet on vapers. The plasma nic level tests are too crude for reliable use in fast response tests.
Best speed test
Vapers can get a better idea of exactly how fast their gear performs by loading it with 45mg strength refill liquid, the strongest available at retail. One pull of this strength will give a far more reliable result as regards the speed measurement than a low-strength refill can. When you feel the hit from 45mg is when vaping hits for you; and when you know that time you can ignore what researchers say it is. You will feel it under 10 seconds assuming your user technique is optimal.
Usefulness of refill strength label
As several researchers have pointed out, the label strength has no relationship to the nicotine delivered to the user, on average. This is because of the large numbers of variables, some of which are:
- The label strength is sometimes inaccurate.
- Hardware has an average delivery efficiency of 50%, so only half the nic will be delivered on average.
- Since hardware efficiency varies between 10% and 80%, then if the hardware used is at the lower end of the scale, then hardly any nic will be delivered at all.
- Most tests show that there is only 10% of the nicotine in ecig vapour compared to cigarette smoke. An example of one test: vapour contained 10mcg nic per puff, cig smoke contained 103mcg per puff.
- User technique can easily halve or double the amount of nicotine delivered. It is easily possible that user A gets double the nicotine from a given set-up than user B.
- There is a difference in individual tolerance to nicotine of a factor of 10. Some people cannot over-vape 6mg strength, and some require 60mg strength to avoid relapse to smoking, and show no signs of OD at all. With this huge variation, it is obvious that what applies to one person may have no relevance to another.
- It is just about impossible, given the variation between people, hardware, refills, and user technique, that two people using the same set-up will measure the same nic plasma level; therefore label strengths are not a guide to plasma nic level.
I tested this myself by going vape cold-turkey for 12 hours. Using 2.4% and NOT holding the vapour in my mouth intentionally, it took a good few minutes before I felt the nicotine for sure. I didn't try a mouth-hold test, but I'd guess at less than a minute if you were an experienced vaper.
I vape 11mg on a dripper at .3 ohms with Dragon nano coils. After like 4 or 5 hits I'm all good, after like 10 or 11 hits I'm dying. Mind you I'm resaturating every 4 or 5 hits. It all depends on tolerance and what you're using. Tanks and vvvw only works for me if it's higher nicotine and that's what I'm trying to avoid.
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However one can increase the nicotine concentration of the eliquid to compensate for the difference. This is bunk science at its worst, we have a product that comes in a variety of nicotine strengths to alter the quantity of nicotine delivered per puff, cigarettes tend to have a more fixed range of nicotine content.
You could effectively exceed the 103mcg per puff by loading up with a liquid that has 10.4 times the nicotine content of the liquid used to get the 10mcg per puff figure, that would result in 104mcg per puff (assuming the delivery method is consistent at higher nicotine concentrations).
I tend to agree with everything else you posted here, I could likely puff without pulling much vapor into my mouth and get nothing out of a 45mg/ml liquid if I cared to do such a thing, I know for a fact I can pull on a 12mg/ml liquid and catch a nicotine buzz in a time comparable to those you mentioned above.
What is a puff anyway? That's like DIY drops right? Like spoon fulls for recipes in Hell's Kitchen? Or is it closer to getting directions to a gas station in Brazil from a New Yorker who speaks to you using Latin words but deep in the hollers Appalachian syntax? Maybe a puff is some percentage of this Lung volumes - Wikipedia, the free encyclopedia or this Lung Volumes and Capacities ?
Me, I like facts, I understand that at a certain point the facts tell you "hey buddy from here on out you just don't have the money or skill or equipment to find anything else out, deal with it" and I'm okay with that.
So if your looking for that nicotine buzz, you have two options as far as I can tell; go long enough without vaping so that your current nicotine strength provides the buzz, or periodically up the strength and get the buzz. It only takes longer to work if your dead or have a high tolerance for nicotine, same as with alcohol.
Maurice
I usually breath in through my nose while inhaling the vapor (mostly for a bigger cloud) and then a small breath in of air to get the rest of the vapor in my lungs and i get a decent buzz off of that. I made an 11mg bottle for a friend and i took one hit and had a massive buzz, just how the stuff works for me i guess.
I've been vaping 12-14mg for the last 3 weeks and never had a buzz, the jitters or the want to vape like crazy cause I want a buzz. Even in the morning I don't get a buzz. Just a peaceful easy feeling.
I find just holding the vapor in my lungs for several seconds seems to significantly increase the "rush" felt from the nicotine. (This is a common technique used by virtually all users of other substances, but seems rare among tobacco and vapor users.) The feeling is not quite as fast as with tobacco, but still takes only seconds to perceive, at least for me.
Well my science is that if I banged analogs the same way I chuff, I would be dead right now. So, vaping delivers less. I have read 50% less and I read the 20% less post. Mechanism delivery is also key in determination.
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