It has been my experience that having not enough hole is bad news in the form of dry, burnt hits, but too much hole is not a problem at all, provided you are using a quality tank with a good seal. I once tested this theory with 8 large holes in a Boge carto in an M1A1 tank, which I vaped for 2 weeks with no leaks or gurgles. Of course, all I had to do was tighten that thumbscrew that the M1A1 has a little too tight to make an iffy seal, and it turned into a flooded mess.
So these days, even though 1 small hole is usually sufficient for most of my concoctions, I always put 2 largish holes in every carto no matter what juice I am using, and just make sure to properly assemble the tank.
One note - for tanks that don't have fill ports like the M1A1, too many holes can cause a lot of juice to be pushed into the carto during assembly of the tank, leaving the carto flooded after the initial assembly. I believe the mini-sub tank you are looking at has a fill port, so as long as it has a good seal and you use that port for refills, this shouldn't be a problem.