Detox of other chemicals above and beyond nicotine should be very minimal by percentage.
Nicotine is the biggie to get right.
Being simplistic, since there is much more to it...Too low, and you get twitchy, and crave...Too high, you get twitchy and possibly run into complications. Dizzy can be from either direction as well.
It's a balance you will need to achieve. It's no different (or not much) when switching cig brands. You end up not liking one but the other is too strong, and yet the other gives you effects you aren't fond of. There are some chemicals lacking in this one, but that one has other issues. This transition is a little more intense than that of a cig change, but the basics are still there.
You'll find it. Hang in!
Ever try going with decaf coffee? Effects are not good. Ever drink a double shot expresso in a tall Columbian?
You'll be all over the board before locking down to a favorite setup.
Pig