Stopped by this thread because I also occasionally have similar issues with my STM. Tastes great, feels great, slowly starts getting gunky after a few tanks, so I re-wick the same coil (thinking I'm doing it pretty much the same way it was when it was working without an issue), enjoy a few awesome super tasty hits, leave the house and start getting those dry, tasteless hits. It sucks as a recent convert from cigs to vaping and even though I carry a Nautilus Mini tank as a backup, it's usually in a desert flavor, and I pretty much rely on my STM to deliver the goods (because it does 95% of the time). So I understand the importance of getting this tank to work properly.
In addition to the good points mentioned (thanks, all), I'm going to throw a couple other things out there. Keep in mind, I'm still pretty new at vaping, so I'm no expert.
1. Out at work or play or somewhere else you can't take it apart and re wick? Close the air hole down to zero (no airflow at all). Don't hit the fire button. Draw on it hard. Watch for a bubble or two coming up into the tank from the juice channels. Do it again. This has worked for me okay. Doesn't fix the problem, but mitigates the issue until you can get home and fix it up.
2. Related to that. Ive noticed that my STM usually goes off the rails and starts going dry when I am out and about. If she's working at home, she continues to chug along great. The only major differences between at home and out are temp fluctuations and tank position. I've taken to keeping my rig close enough to my body to mitigate much of the temp problems, I think, which leaves tank position. Love the STM because i doesn't leak. That also means it sometimes falls down sideways in my inside jacket pocket. Why I think this matters is air. It was something I noticed on my Lemo Drop, which is has similar juice channels. I could sometimes see an air bubble just inside the juice channel. It's just sitting there right under the lip of the natal chimney part that hits the deck. I'll cold hit (that's my new gaping lingo for the day I'm using for the act of drawing on the device with no power as described earlier) , which usually clears things up. But there he is, like a bouncer at the door. The juice can't get past him. To get him out of the way, I hold the device this way and that, blow, suck and do whatever I can to get him to either go in or out. Eventually it works. I've seen other threads where people have mentioned getting airlocks that affect wicking. I don't know if this is the same thing. For me, it usually happens with the thicker juices, but even the thinner ones have had this issue on occasion.
Good luck