Mouth cancer
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Honestly I don't think there has been much research on safety issues with ANYTHING in regards to e smoking...
Even if inhalation of PG or Nicotine caused mouth cancer, I'm sure it would take quite awhile before it showed up and e cigs are just too new to have any significant findings at this time...
Even if inhalation of PG or Nicotine caused mouth cancer, I'm sure it would take quite awhile before it showed up and e cigs are just too new to have any significant findings at this time...
I do not think it should be a serious concern. Think about NRTs; gums, lozenges and inhalers, in particular. All of them are nicotine being absorbed through the mouth.
I do not think it should be a serious concern. Think about NRTs; gums, lozenges and inhalers, in particular. All of them are “nicotine being absorbed through the mouth”.
'Cancer risk of nicotine gum and lozenges higher than thought' - Times Online so who knows
But the NRTs are indicated for short-term tapering anyway, not chronic long-term use. You're supposed to take an NRT over a 6-8 week or whatever tapering period. That short of a time smoking analogs or chewing tobacco isn't likely to give one cancer, either.
There has not been one reported case of mouth cancer from vaping. And there has been vapers for 5 or more years. Hope this helps a little!!
There has not been one reported case of mouth cancer from vaping. And there has been vapers for 5 or more years. Hope this helps a little!!
5 or more years? Really? Im thinking it is more around the 3 year mark at MOST
Nicotine gum is chewed and stays in the mouth .I don't see how the risk could be any higher than with analogs . Right?
Nicotine is not carcinogenic. Tobacco is. If someone has been using tobacco for many years, how can you attribute cancer to an NRT only?
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A careful read of the news article reveals that they really didn't discover much. Maybe and could be all over the place. What they are saying is that if you already have a pre-cancerous lesion and you use nicotine, then MAYBE there might be a problem.
Well for dang sakes, they sure pulled that article outta their as..er...noses. I read study after study on nicotine, as well as smokeless tobacco, and it's gotten so much easier to sort the real from fluff. NO REAL EVIDENCE SUPPORTING A LINK BETWEEN NICOTINE AND CANCER OF ANY KIND EXISTS. That article is one of thousands being circulated with misinformation, on the assumption that the readers won't look for facts. Good or bad, I just want the facts to make informed decisions on my life choices. No real facts to be found in this one.....
" It is not as potent a carcinogen as other chemicals found in tobacco smoke........" Fact: Nicotine is not a carcinogen!!!
janetda said:
It bothers me he said it raises the risk of oral cancer and that it's possible for smokers to have developed these lesions and not even know it. Even if nicotine only worsens the situation from pre-cancerous to cancerous, and doesn't cause the problem in the first place, it's still worth studying. Maybe for people who never touched cigarettes ever and go straight to NRT, and/or don't develop this mutation through any other method, then it's not relevant. For ex-smokers like us, it's worth reading up on.
Regardless, the OP's question was about research being done on orally absorbed nicotine and cancer. These study results were published and the story was carried in quite a few places. Google it.
If you don't care for the way the information is presented in any of them, you can read the study yourself PLoS ONE: FOXM1 Upregulation Is an Early Event in Human Squamous Cell Carcinoma and it Is Enhanced by Nicotine during Malignant Transformation
However...it's not like they "didn't really discover much" and it's not like the article is, "being circulated with misinformation, on the assumption that the readers won't look for facts" ...the study is there and there are tons of articles on it if you prefer to read them instead.
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No, vaping has been going on in other countries longer than here in the usa.
Katmar: The e-cig was patented in 2004. It did not appear on any market until 2007. It has not been in widespread use anywhere for more than three years -- and real use for about two years. We do not know long-term consequences.
As for nicotine -- it is not a carcinogen. Many wish it were, so they could damn it directly, but it is not. If someone develops an oral cancer, it will not be from nicotine. Besides, almost everyone using an electronic smoking product came from a history of smoking cigarettes, a practice known for oral cancer causation.
How would anyone ever know the real culprint behind an e-smoker's oral cancer?
If you read all the studies on PG and nicotine, you can logically conclude you are doing yourself good by e-smoking, the exact opposite of smoking cigarettes. Nicotine has many benefits; PG vapor has many studies showing its anti-bacterial benefits.
As for nicotine -- it is not a carcinogen. Many wish it were, so they could damn it directly, but it is not. If someone develops an oral cancer, it will not be from nicotine. Besides, almost everyone using an electronic smoking product came from a history of smoking cigarettes, a practice known for oral cancer causation.
How would anyone ever know the real culprint behind an e-smoker's oral cancer?
If you read all the studies on PG and nicotine, you can logically conclude you are doing yourself good by e-smoking, the exact opposite of smoking cigarettes. Nicotine has many benefits; PG vapor has many studies showing its anti-bacterial benefits.
Fart...I'm on dial-up and the server keeps timing out when I try to load the study
. I'll do it at work. Thanks satoshi, I'll read it.
Perfect reply! I read an article that Sweden has had a large number of Snus users for over 20 years with no reports of mouth or throat Cancer. If thats true I think nicotine can be ruled out as the culprit. According to what I've read it is the carcinogens that develop during the fermentation process of the tobacco that is the main cause of all tobacco related cancer. This is just what I have read, I am far from an expert on the subject.
Actually, there are quite a few long term studies on Swedish snus, with the most concise ones lasting a period of 40 years. And you're right about the fermentation process. Swedish snus is pasteurized and why it's safety is unparalleled with other types of tobacco. It's been used for over 200 years and the Swedish government no longer requires any type of warning labels on it.
Thanks for the info, TB. I remember reading in here somewhere about ecigs in use for about 5 years in other countries. Not about wide spread use, though.
Alrighty satoshi, I got it read......man, you owe me......at a rather large expense to my diminished assortment of brain cells. DVap, you'd eat this one up.......
"However, in the case of SVpgC2a cells, the highest dose of nicotine (10−2−3 M) and arecaidine (10−3 M) showed significant decrease in cell viability (Fig. 4DF) indicating that the oral premalignant cell line is generally more sensitive compared to the two HNSCC cell lines. "
Not to take away from the complexity of this peer-reviewed research, they've labeled it a "co-carcinogen" about midway through, meaning it's not a carcinogen. Meaning it doesn't cause cancer. It does, however, aid in cancers growth, sorta like sprinkling some Miracle Grow on a plant. But then Miracle Grow doesn't make plants appear without a seed to feed. Not saying it's not a legitimate study, I can't understand a lot of it and I'm sure several tax dollars went towards it, so it must be ok. But in the case of abnormal cell growth or death, I'm more concerned about the everyday foods I eat much more than nicotine. I'd need to see more than this to raise my eyebrows, but it's a good study......I think...........
"However, in the case of SVpgC2a cells, the highest dose of nicotine (10−2−3 M) and arecaidine (10−3 M) showed significant decrease in cell viability (Fig. 4DF) indicating that the oral premalignant cell line is generally more sensitive compared to the two HNSCC cell lines. "
Not to take away from the complexity of this peer-reviewed research, they've labeled it a "co-carcinogen" about midway through, meaning it's not a carcinogen. Meaning it doesn't cause cancer. It does, however, aid in cancers growth, sorta like sprinkling some Miracle Grow on a plant. But then Miracle Grow doesn't make plants appear without a seed to feed. Not saying it's not a legitimate study, I can't understand a lot of it and I'm sure several tax dollars went towards it, so it must be ok. But in the case of abnormal cell growth or death, I'm more concerned about the everyday foods I eat much more than nicotine. I'd need to see more than this to raise my eyebrows, but it's a good study......I think...........
Hello, sorry if this switches the topic for a moment. I was looking at this article because of the mouth cancer title. I did have a question, someone mentioned that the nicotine in vaping is absorbed through the mouth when vaping.... do the nicotine is not absorbed through the lungs at all? I vape both pg and vg and sometimes a mixture.
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