nicotine absorbtion

over time, with any drug, one develops a tolerance.

 

You are right....you aren't getting 36mg. I believe the few studies we do have show you are actually absorbing only 10% or so.

The remainder goes to a garage in Buffalo....

 

Yeah, but still not enough studies have even been done to prove that. We need many more conclusive studies. Some even speculate we aren't getting any nic. Personally, I am wondering this myself. Which answer is it?

 

Wouldn't it be something to find out we all where paying for the most costly part of the juice being the Nic and find out we might as well be vaping flavored cool aid, hahaha
We are getting Nic, there is know don't in my mind, however the absorption rate is what the studies need to tell us and at what Voltage, I really believe higher voltage like 5-7.4 give you a higher intake of the nic in the juice than the lower 3.7v. Time will tell.

There is a new study that just started which might give us some info but not all. I also don't feel we will ever have these studies until this Govt we have gets more involved with a way of taxation, then the big boys will jump in and sink the big corporate money into this and the studies will then get completed for sure since the ones that pay for the studies are the ones that will be selling us our goods, which will have pluses and minuses to what we can and can't vape and how we do it.!!

 

I think its impossible to not be getting any nic at all unles theres none in the juice. I am unsure about if we get less/more or the same nic levels than cigs. You have to consider the other additives in cigs as well. Is it the pure nicotine we are feeling or a drug/carcinogen cocktail from the regular cigs compared to the PV's. The only thing I know for sure is that the PV has definitely helped me.

 

The two New Zealand studies both arrived at 10%. One was relative to cigarette delivery....and I forget exactly how the other 10% figure relates except to say that absorption is being shown to be very low. On the other hand....the zero-nic study which the good doctor took a beating for here in the forums was eventually shown to be wrong by the doctor himself. Yet even in his follow up experiment he claimed to not get the increased heart rate that should have accompanied the nicotine absorption, but did show it had absorbed in some ammount into his blood stream.

To add to the confusion is all the different ways people inhale and in my case....a constant wondering if the China manufacturers are maintaining the nic levels as marked. If they can screw up the flavoring....they can screw up the nic....right?

 

I've been thinking about just stopping using ecigs for a few days to see how I feel physically and psychologically. I remember reading in a couple different places that people just stopped vaping cold turkey and didn't even feel withdrawal. I think a big part of this is psychological. I also am a firm believer that smoking increases the nic absorption rate and vaporizing nicotine is a less effective delivery method.

I think a major factor that comes into play when coming off cigarettes using ecigs is psychological effects. We see the smoke, feel the throat hit, select nicotine, etc. While we may not be getting as much nic as before, we think we are, which is all that really matters. I doubt any of my rambling just made any sense.

 

Makes perfect sense to me because I was able to quit analogs AND nicotine the day I picked up vaping with only the slightest bit of inconvenience. There just might be something to your theory.

 

The psych issues are most definitely at play and part of the reason for the dismal performance of gum and patches (also low nic). I still smoke a couple cigs per day (just out of spite for the smoke nazis) and they will give me a buzz. Something that vaping 47mg all day doesn't do.

 

Everyone makes sense to me, but I'm easy. All I can add is that I remember very well how that first ML of the day, coffee in hand, would make me dizzy doozy if I smoked it too early or too hard. Full-on head rush, which I've never gotten from vaping at 18mg. Something's different, but is it the nic level, the absence of 4000 other chems, or another factor? Looking forward to the research when it comes.

 

Here's the real catch....

If the studies show we aren't getting much if any nic....then the worst thing they could do is tell us and ruin the placebo effect....LOL

 

I believe that we are getting nic from vaping and, anecdotally, it seems to be at the same levels as analogs; depending on type (Lights, Full Flavor) and amount smoked. I used to smoke a pack of "Lights" a day, and when I switched to V4L I began by vaping 2 - 3, 24mg cartos a day. I say "switched" and not "quit" because that's how it felt to me. I could switch from analogs to carts and back and I would not get that "buzz" when smoking the analog. During the first couple of months I would only smoke about 1 analog / week, so I don't believe I was retaining my tolerance for cigarettes.

Now that I've moved down to 18mg I will still have an analog every once and a while. With my body being used to 18mg (2-3 carts/day) I do get a very slight buzz when smoking a cig.

My 2¢.

 

I've confirmed the nicotine concentration for some vendors I've analyzed - but some other vendors fall nearly 30% shy. Due to what I assess as the commercialism of ECF and an absolute lack of cooperation in the vendors I've hit-up, I don't feel comfortable publishing results because my sample sizes have been too limited. Destroying someone just because the sample was corrupted and the number of samples too small to be of statistical significance bothers me - so I just make generalized statements: Maybe yes, maybe no. Some are pretty far into the "no".

I'd council anyone who thinks they're vaping over ~20mg/ml analyze their juice and supplier(s) to their own satisfaction.

 

I vape 36 mostly too, though I'm still using up some old 24 stock as well. I know I'm still getting nic for 2 reasons.

A. Without nic I get baaaaaaaad migraines. Since vaping I have yet to get a migraine.
2. There have been times where I've been offered a cig (non-FSC of course) and smoked it. Despite the fact that I went 3 whole mos w/o a cig when I smoke that cig (full strength) I didn't get a buzz.

While I admit that the placebo effect could account for alot of things, the lack of migraines is just too much for me to ignore. In the past when I've stopped smoking the magic mark was about a month after cessation in which the massive migraine would hit. If anything I should've psyched myself into having one; I was expecting it so much at first.

 

I'm glad my rambling made sense! hahaha. I really wish they would do more studies. How are they gonna go around trying to ban them in all 50 states with no evidence they are bad for you? I love the article I read proclaiming ecigs don't deliver nic. I think that was an article payed for my the tobacco companies to sway people from starting ecigs. Something is fishy about that. If there is no nicotine, thanks for the excellent placebo effect and getting me of cigs without even trying.

I know I am getting nicotine, but how much I get with every puff is a mystery. That's another reason I stick with v4l and a few others, I know they are putting nicotine in there juice. Imagine how much money some juice companies can make just selling you flavoring at 10-20 bucks a flavoring. Not insinuating any particular vendor, but there are some bogus vendors out there as we all know.

Yep, I'm paranoid.

 

Much of this discussion is moot. There are too many variables

From a given amount of nicotine in a cigarette you will get a higher absorption rate due to other gasses and chemicals in the cigarette that enhance the absorption rate. CO binds with nicotine and the CO is absorbed more readily in the lungs. Just one example.

As has been pointed out, the way you inhale, the length of time it stays in your lungs and many other factors make the differences in absorption between any 2 people different. Not to mention differences in phsiology between people.

If whatever amount of nicotine in your E-Cig satisfies you and keeps you from using analogs that's what counts.

Maxx is a special case.

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