Quick answer is practically all of it, but slower than with ciggies.....
From what I can gather from lab. testing on juice & vapour,
for example LibertyStix latest testing of JC juice:
http://www.libertystix.com/LibertyStixLabAnalysis072309.pdf
The gas-chromatograph of vapour in that report (fig 2) shows a large spike of nicotine
= 3-(1-methyl-2-pyrrolidinyl))-pyridine)
and a much smaller spike of the (probably) primary heat breakdown-product
= 3-(1-methyl-1H-pyrrol-2-yl))-pyridine (or at least something very similar).
So showing most of the nicotine in the vapour is intact.
Also the tests in the thread:
http://www.e-cigarette-forum.com/fo...ow-much-nicotine-destroyed-during-vaping.html
Shows that the total amount of nicotine present in the juice,
is still in the vapour as nicotine & (the smaller amount) of breakdown products .
So the answer is that you get nearly all the nicotine, that is in the juice, into your
mucous-membranes (in your lung / mouth) still as nicotine, but it's all 'wrapped up' in PG or glycerol
That just leaves the question of how much/quickly the nicotine gets from there into your
blood stream (say compared to the high effeiciency smoke in ciggies).
The answer to that appears to be 'most of it, but significantly slower'.
It's almost certainly released quick enough, such that the half-life of nicotine in the body (about 2 hours),
can't remove it before you get most of the effects.
I think of vaping (in terms of nicotine uptake & rate) as 'slow purified cigarettes', or very fast patches.
Also I think/feel that because of the slowness (c.f. ciggies), people tend to take in more nicotine than
they would when smoking, increasing their nicotine 'resistance' (& possibly dependence) in the process.
Then there's the question of what else comes from ciggies that you 'miss',
the thread linked by pianoguy above really shows some good info on that
(e.g. all the other 'minor' alkaloids apart from nicotine)
The 60% nicotine loss (40% recovered) mentioned above by pianoguy is actually a very low figure
that really should be 'at least 90% recovered, nearer 100% when atomizer coil is kept wet/gurgling'.
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(not sure if this is the right place for all this, but the question was right)
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