There is little reason if ever to go with 2x 18350 vs 1x 18650. Battery innovation has been happening far and away the most at the 18650 cell size so you can get better performance and capacity out of a 18650 per cell size than any other size at this time.
As the others have noted, you gain no capacity when you run in series, or when you run in parallel, you only get 2x the capacity. Now there is a little to be gained by the modified current draws caused by these configurations, 7.4v nominal requires far less amperage than 3.7v nominal, and with parallel cells the amperage is divided between the two cells. However this does not make up for the nearly 4x greater energy in a 18650 cell.