I just got order of RY4 straight PG. I was using and have always vaped 50/50 and never had any allergic reaction. So far so good on straight PG. I think I would of had reaction before even with 50/50?? Hopefully this straight PG will vape better than the 50/50 RY4 did it the Kanger T4 Clearomizer and I might even switch my 555 to a straight PG if it does vape better...make clearos last longer..