Propylene Glycol origins?

[Mrez]

Alright vaping friends, I couldn't find the appropriate history for Propylene Glycol so I thought I'd check with the ECF Hive Mind.

Short History, I get into a lot of heated discussions with people on pseudoscience vrs actual evidence. The topic of vaping came up with one of them, and when I mentioned that PG was in ecigs, I ended up faced with alot of only partially true information. He was convinced that even in minute amounts PG was cancer causing (more so then analogs) and that alone would keep him from vaping (not the he should anyway, he's a non smoker). I mentioned to him that all of the appropriate regulatory agencies recognize PG as generally safe for consumption, and it is used in a number of products from food production, pharmaceuticals, etc. Dosage makes the poison, etc (yes harmful in large quantities, but not in the amounts that we are regularly exposed to, vaping or otherwise).He said it hasn't been around long enough to make that determination and it's origins as a refrigerant automatically exclude it from consumption.

I know its been around for a while, but I couldn't find any information on how long it's been around. Does anyone have any citable sources?

 

[stevegmu]

It is used in a number of food and hygiene products and some medicines. I don't know of any studies showing is is perfectly safe to vaporize and inhale, over and over again over a long period of time...

 

[skoony]

It is used in a number of food and hygiene products and some medicines. I don't know of any studies showing is is perfectly safe to vaporize and inhale, over and over again over a long period of time...

you do to Steve. its been used in inhalers and considered safe for decades.
mike

 

[Stosh]

Here's a link for a study done, which found no toxicity.. TESTS FOR THE CHRONIC TOXICITY OF PROPYLEXE GLYCOL AND TRIETHYLENE GLYCOL ON MONKEYS AND RATS BY VAPOR INHALATION AND ORAL ADMINISTRATION done in 1947.

The Journal of Pharmacology is a reasonable source also.

 

[stevegmu]

you do to Steve. its been used in inhalers and considered safe for decades.
mike

I had terrible asthma as a kid. Petu'lka and Nikola also have asthma and I have seen them use their inhalers on a number of occasions. I have also seen the 42 paragraph warning pamphlets which comes with them and don't recall any type which is heated before inhaled. Heating things can change their properties...
Just because something is in a medication doesn't mean it is safe; it just means the disease is worse...

 

[Mrez]

It is used in a number of food and hygiene products and some medicines. I don't know of any studies showing is is perfectly safe to vaporize and inhale, over and over again over a long period of time...

Yeah, thats what my brief google search showed, and is consitient with what I had read previously, and repeated to my friend. For us as vapors, we are lacking the critical info regarding inhalation over long terms at various percentages. But over all it is recognized as safe.

you do to Steve. its been used in inhalers and considered safe for decades.
mike

That is pretty much exactly what I said, when he responded that it hasnt been around that long...I couldn't find a source to track back the earlier studies and origin of the product.

Here's a link for a study done, which found no toxicity.. TESTS FOR THE CHRONIC TOXICITY OF PROPYLEXE GLYCOL AND TRIETHYLENE GLYCOL ON MONKEYS AND RATS BY VAPOR INHALATION AND ORAL ADMINISTRATION done in 1947.

The Journal of Pharmacology is a reasonable source also.

Thanks, thats what I was looking for. So it's been around since at least the late 40's, probably can be inferred that its been around before that if it was being studied in 47. Thats decades in my book, and if there has been no definitive causal links since then...thats pretty compelling evidence.

 

[Robert Cromwell]

you do to Steve. its been used in inhalers and considered safe for decades.
mike

Inhalers are very small doses. Not 30 ML or more per day.

 

[stevegmu]

Inhalers are very small doses. Not 30 ML or more per day.

It also isn't heated. The last study was done in 1947. Back then wasn't smoking cigarettes also considered safe?

 

[Robert Cromwell]

It also isn't heated. The last study was done in 1947. Back then wasn't smoking cigarettes also considered safe?

cigarettes where considered healthful not just safe.

 

[stevegmu]

Thanks, thats what I was looking for. So it's been around since at least the late 40's, probably can be inferred that its been around before that if it was being studied in 47. Thats decades in my book, and if there has been no definitive causal links since then...thats pretty compelling evidence.

What applications has it been used in where it is heated, vaporized and inhaled since the 1940's?

 

[Robert Cromwell]

I vape about 60 days worth of inhaler PG in one day and I am a tootle puffer. Who does 40% PG...

 

[Robert Cromwell]

What applications has it been used in where it is heated, vaporized and inhaled since the 1940's?

Aside from Vaping? Fog machines?

 

[stevegmu]

Aside from Vaping? Fog machines?

I think fog juice is something else, like glycerine or mineral oil...

 

[Robert Cromwell]

I think fog juice is something else, like glycerine or mineral oil...

Might be, Never vaped the stuff.

does it come in Cinnamon Danish swirl flavor?

 

[Mrez]

What applications has it been used in where it is heated, vaporized and inhaled since the 1940's?

None that I am aware of. The discussion left the vaping issue pretty quickly and went towards the overall safety of PG in regular products.

 

[stevegmu]

None that I am aware of. The discussion left the vaping issue pretty quickly and went towards the overall safety of PG in regular products.

Usually does. Just like its safe to eat food flavorings, so must be safe to heat and inhale them over and over again in large quantities...

 

[Robert Cromwell]

I would vape a steak but can't fit in in my Evod.

 

[Shae McAualy]

Might be, Never vaped the stuff.

does it come in Cinnamon Danish swirl flavor?

I don't know about Cinnamon Danish swirl, but there was one that was cotton candy at a party I went to.

 

[crxess]

Well, if Scientist were really interested, the Products have been around for 9yrs. that I can establish.
Gubment - to new -to new - we just don't know!!!!
Reality check, Government ignores to the last minute then Crys Wolf.

Our history

E-liquid production for Electronic Cigarettes since 2006.
Also one of the largest manufacturers of e-liquids in the world.

 

[stevegmu]

Well, if Scientist were really interested, the Products have been around for 9yrs. that I can establish.
Gubment - to new -to new - we just don't know!!!!
Reality check, Government ignores to the last minute then Crys Wolf.

Our history

E-liquid production for Electronic Cigarettes since 2006.
Also one of the largest manufacturers of e-liquids in the world.

I wouldn't trust pet food made in China, let alone inhale something made there...