The power (watts) is a big factor in choosing a wire gauge for a particular resistance build. I'm going to assume you want to be in the 30-50 watt range with a Mutation X, that you have a regulated
mod instead of a mechanical and use the Steam Engine coil building calculator to help me design the builds.
The single coil 0.5 ohm build: A 6/5 wrap coil with 24 gauge Kanthal on a 2.5 mm pin will work for you between about 20-50 watts, but it will be close to burning
juice at 50 watts and will probably do that at around 55 watts.
Here it is in SE at 40 watts.
The heat flux of 353 mW/mm² (miliwatts per square mm of coil surface area) is safe and the heat capacity of 47 means it will give you almost no heat up delay even with a cold coil. If you increase the watts in the heat flux area to 50 the HF goes up to 442 which is why I think it will be close to burning
juice at 50 watts. If you want to use higher power switch to 22 gauge Kanthal and for lower power use 26 gauge.
The dual coil build: Two 5/4 wrap coils with 28 gauge Kanthal on a 2.5 mm pin will work for you between about 20-48 watts and will probably start burning juice at around 53 watts. Coil heat up time is minimal.
Here it is in SE.
Two 8/7 wrap coils with 26 gauge Kanthal on a 2.5 mm pin will work for you between about 30-90 watts and will probably start burning juice at around 100 watts.
Here it is in SE.
With a mech mod 0.5 ohms will make about 30 watts with a charged battery and be down to around 20 watts by the time battery voltage drops to about 3.6V. If that's what you're doing I would start with the same 24 gauge build for the single coil setup and the 28 gauge build with dual coils.
Hope that helps.