I would say first, set yourself a $$$ limit.
Then, decide what you are looking for in a liquid. Do you want sweet, fruity, tobacco etc. If you want something that will just totally blow you away with flavor, theres cinnabomb. For most people, that seems to be the one that gets them, although I would say judging from just reading posts that the fire n ice is a good choice as well. After that, my second juice in my cart would be arctic ice. Its a super strong menthol, i mean like a vicks vapor rub strong, which I happen to love by itself, but I also use it to add to flavors. For some reason adding a touch of arctic ice to any fruit flavor, makes the fruit pop. I use cartos so lets say i want peach. Peach by itself is very good, but 16 drops of peach and 4 drops of arctic ice and the peach pops.
So you should have a cinnabomb or fire n ice, and then the arctic ice...those 2/3 are the must haves. Cause what you can do with the arctic ice, you can also do with the cinnabomb, add them to other flavors.
Now it gets harder...keeping your $$$ amount in mind, go through each of the categories and start adding them to your cart. You can either go start to finish and then remove to hit your $$$ amount, or you can just add until you reach it. I like to "window shop", meaning I go through the website, all categories and add to my cart the flavors I want to try. Those flavors might sit in there a week or so, until I am ready to buy. Once its time to submit an order, I see how much $$$ my total is, (it's here that I usually have a minor heart attack) adjust my cart to a more manageable amount and send off my order.
Keep in mind, VB always has FREE shipping or they PAY YOU TO SHIP!!! what this means is, the standard shipping is $3.95, but VB always throws in a free 5ml sample with your order, and a 5ml sample costs $3.95 so its like free shipping. Go over $59 and the shipping is free, but they still throw in a sample so its like they are paying you to shop at VB. how sweet is that???