I think I'm the organic/natural nut job on the forum, at least I haven't run into anyone more particular than I am. So here's what I do.
I use 100% USP Kosher VG. If I could find organic I would. VG is all natural and made from plants. PG is a man made petrochemical. There is a ton of research showing PG is fine. Many are happy to use it and if it keeps you off analogs, more power to you. It's a personal choice and mine is to avoid PG.
I use USDA-certified organic flavorings from Nature's Flavors and mix my own liquid. I do not use any artificial sweeteners or ingredients.
Before I mixed my own, and even now I buy from Virgin Vapor, which follows the same principles. My flavorings do contain alcohol, but you can get alcohol-free juice in Virgin's Absolute line, and their stuff is amazing.
The other potential risk is diacetyl, which is often added to artificial flavors, but also occurs naturally in the creamy, buttery flavors. There is evidence to suggest that inhaling diacetyl is not good. However, the tiny amounts that occur naturally in natural flavors is far below the threshold supported by that evidence. You can avoid it entirely by avoiding the creamy flavors.
So, in my research I've found Virgin Vapor's Absolute Line to be the purest, "safest" juice- that also tastes amazing. Personally I chose to mix my own, so I have even more control. If you want to learn about DIY check out the DIY subforum under E-Liquids.