Throat hit and nicotine absorption

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Astronomer

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That is an excellent question.

I don’t think for one moment that Throat Hit has anything at all to do with Nicotine absorption. ( but that is an opinion, I don’t know ) That is not to say however that the absorption rate might be different between PG an VG however.

I don’t think there has been much ( or any ) study of nicotine absorption on E-Cigs, PG or VG or what have you. So I don’t think we can reliably say if there is a difference.

I do know we are getting some nicotine as in a health screen I tested positive for nicotine.

I am using a 80/20 PG/VG mix

I suppose what I am saying is that I am not sure there is a definite answer to your question, just a whole lot of opinions and personal experience.
 

dormouse

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TH is just an effect of nicotine's skin irritation and the heat of the vapor. PG lets TH and flavor (including nicotine's pepperiness) through well. VG is thicker and dulls the TH and flavor while adding more visible and persistent vapor. Whether VG actually effects nicotine absorption is a good question since it does seem to protect your skin more from nicotine's irritation. No idea.

Why are you vaping 100% VG? Most people vape blends like 70pg/30vg or 80pg/20vg or 50/50. There is usually some blend level that will get rid of irritation for a person while leaving enough TH and flavor. The exact ratio per person will depend on the heat of their ecig's vapor, the amount of nicotine they use, the amount of TH they want.
 
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Zal42

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Like the others, I don't know. Its entirely possible, but it's equally possible that you might simply associate throat hit with getting nicotine -- I know I did when I first started vaping! If it didn't burn my throat like a cigarette, I didn't find it satisfying. Now, th isn't so important to me for satisfaction.

You could try getting higher-nic juices and see if they satisfy you better. I'd be very interested in your experiences with this.
 

Zal42

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Well with pg 18 mg was to much for me and I got a head ache. Now I'm at 24 mg with vg and I can't tell that theres any nicotine at all. I was reading that people didn't get th when they added pga to a none nicotine liquid. So I thinking that the pga would bring the nicotine out. I'll go to the store and try it then report back.

It's not unusual for nic needs to change shortly after starting to vape, too.

About pga, personally I've found that it doesn't add any appreciable throat hit whether or not there's nic in the juice. Others have different experiences. Perhaps some people's throats are more sensitive to alcohol than others. Some people who get little effect from pga may be mistaking the th nicotine itself has for the effects of pga and thus thinking that it only works when nic is present.

It's worth giving it a try!
 

tsbrewers

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I've been vaping with alcohol, it helps only a little. It turns out it's illegal to sell pga in MN so I just used 15% vodka. the headache was probably from the pg. I'm going to try a little more nicotine and see how that gos.

My local stores have Everclear, so maybe it is a county thing?

Brew
 

BatPony

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Throat hit is generally caused by both the nicotine as well as the propylene glycol. If you've ever stuck your face in front of a fog machine, you've noticed the pg side of things.

Vegetable glycerin, chemically speaking, is a less efficient vehicle for the nicotine. It's not readily absorbed by the tissue in the respiratory tract and therefore delivers less nicotine per hit. The lack of absorption is partly responsible for the increased vapor output. There are also some potential (and I mean POTENTIAL) hazards of using pure vg liquids. Just before vg reaches its boiling point, it decomposes and produces acrolein. If you're not familiar with this chemical, it's incredibly...incredibly toxic. While I've never seen, or heard of an atomizer reaching a temperature high enough for this to happen, mod folk and those vaping their carts dry should take note of it.

I have no idea what the potential hazards of mixing ethanol into the liquid might be. I imagine that its addition may lower the boiling point of a mixture with vg and may increase vaporization efficiency. Then again, I'd need to conduct some experiments to determine if ethanol causes unforeseen chemical decompositions, or is involved in any other side reactions with the nicotine, pg, vg, etc. before I could be sure. Any other biochemists out there that have some insight on the matter?
 

dormouse

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PGA and other super-high alcohol liquors are illegal to be sold in some states. I had to go to another state to get some.

There is also QHit, an additive by Flavourart (Liberty-flights.com, FreedomSmokeUSA, OneStopDIYShop all have it - but I do not know if there is an PG in it). And FreedomSmokeUSA has Pepper juice and flavoring.

You could try AveJuice's VG's. That Boba's Bounty had a strong throat sensation for me (and from the after burn to me it seems like chili juice or something)
 
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Kent C

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I was wondering if th makes you absorb more nicotine?

That reverses cause and effect ... kinda. Nicotine causes throat hit - the more nicotine the more intense the throat hit. And while you may be absorbing some nicotine through contact in the throat - most of the absorption is happening in the lungs. So the more nicotine (and vapor which carries it), the better absorption and how much absorption takes place will vary from individual to individual.
 

subversive

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And while you may be absorbing some nicotine through contact in the throat - most of the absorption is happening in the lungs.

So we are, in fact, absorbing it through our lungs? I read that with vapor it is almost all absorbed in the mouth because the molecules are too large for lung absorption. I keep hearing two different things, don't know which is correct.
 

Kent C

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So we are, in fact, absorbing it through our lungs? I read that with vapor it is almost all absorbed in the mouth because the molecules are too large for lung absorption. I keep hearing two different things, don't know which is correct.

I guess you'd have to have medical tests to actually find that out and I do know a lot can be absorbed through the mouth - like snus, chew, etc. but depending on how deep you draw down it would seem to me that the chances of lung absorption would be better - I may be wrong on that - the point basically being that it is the nicotine that causes the TH and the increase in nic causes an increase in TH.

What's your source on the 'molecules being too large'?
 

Kent C

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Just from random posts throughout various forums on the internet, no link for you, sorry : (
I realize this isn't an exact science yet, wish there was more research out there.
If I do come across the original place I saw that posted I will link it here.

Didn't mean to put you on the spot but I hadn't run across that myself and thought maybe you had seen it recently. The 'it isn't an exact science' is probably the best 'summary'.
 
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