There is no lock out on the adjustment buttons for the Vamo V. If you are putting it in your pocket then you'll want to check it each time you take it out before hitting the fire button. If you leave it in a cradle, or coffee cup on your desk, you should have no problem.
I would recommend switching to a rebuildable, but I like fiddling with things and trying out different options. I'm also a cheap ....... and I'd rather pay $5-6 for a spool of 100' of wire and a bag of cotton balls than pay a dollar everytime I need a new coil.
With rebuildables I have yet to ruin a coil. I've burned a few wicks, but that's no big deal. My overall favorite is a Kraken with cotton wick and a single coil (1.6-3.0) ohm on top of my Vamo V or my Smok SID. Both mods have their pros and cons. Vapor is good, flavor is good, it's simple, and I'm happy. I have a pile of EVOD2, and Vivi Nova clearomizers that are getting lonely in their storage block. I don't much care for them anymore. I hardly ever even use my Naultilus either, but at least they let me adjust the airflow.
Edited: I forgot to add that you can just hit the fire button 5 times (sometimes 6) before stashing it and it won't adjust on you. You will have to wait for about three seconds when you pull it out and hit the button 5 more times to turn it on before you can hit the juice, but you'll save the coils that way.
