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You’re a mammal ( I assume) so no. Your core body temp is going to be the same temperature whether it’s cold outside or not.
This ^^ but i'll add the fact that juice gets thicker in the cold and make your wicks....wick less ? if that makes sense, i use a dripper and almost at the point i have to squonk every puff lolz.
how cold is what you consider cold??? where I live 50F is cold... 21F is unreal and only considered to be something found at the top of the world 
Has to be at least 80 for me to be comfortable. Unfortunately, it's 52 inside my camper at the moment.
The vape won't build up in your lungs at any temperature, that's just not how things work.
Depending on how cold trying to keep your vape warm somewhere on your person is likely a good idea. When it gets below 65 degrees (F) around here, I note that it IS harder on my batteries as I have to "warm" them up by using them, so sometimes it will take a few inhales to even get the vape going. Using high VG juices can also present a problem as VG does get thicker with cold and also may be slightly harder to get your vape going.
I mostly have the opposite problem where I won't leave my vapes in the car in the summer, even if I'm stopping for a minute as my car can heat up to rather high temperatures fairly fast and I worry about battery explosions. It's probably unlikely but it is *possible*. Vape equipment does perform differently in different environments, though, so it's often a helpful question to ask about it, and gear generally.
Welcome to ECF.
Anna
Depending on how cold trying to keep your vape warm somewhere on your person is likely a good idea. When it gets below 65 degrees (F) around here, I note that it IS harder on my batteries as I have to "warm" them up by using them, so sometimes it will take a few inhales to even get the vape going. Using high VG juices can also present a problem as VG does get thicker with cold and also may be slightly harder to get your vape going.
I mostly have the opposite problem where I won't leave my vapes in the car in the summer, even if I'm stopping for a minute as my car can heat up to rather high temperatures fairly fast and I worry about battery explosions. It's probably unlikely but it is *possible*. Vape equipment does perform differently in different environments, though, so it's often a helpful question to ask about it, and gear generally.
Welcome to ECF.
Anna
Welcome and glad you joined.
I would not be surprised that it would show trace amounts in your lungs after vaping. Not sure if e liquid would build up though. Good question.
You make thicker (more dense) clouds when vaping in the cold. Try it. It's like creating your own smokescreen so your neighbor will stop spying on you when you're just watering their plants through what you created naturally that science would call urine.
once atomized the e-liquid's reaction inside the body is the same regardless of air temperature in your environment. Like most of the good folks who have responded to this have stated the only real negative effects that environmental temperature really have on your vape is how long it takes to get the coils doing their job, the consistency of your e-liquid, and the devastation that the cold presents in battery performance. Now one interesting piece of trivia for you that nobody here has mentioned is that if you are traveling by air and use a tank system atomizer, drain your tank back into your juice bottle before boarding your flight otherwise the change in atmospheric pressure during your flight will break the vacuum in the tank causing it to drain the juice all over the place in your pocket or carry on bag. I never had anyone tell me this, and unfortunately found out trial by error when I flew to Scottsdale for a corporate training seminar a few years back and what a mess it made in my leather jacket. Outside of that winter and summer have equally troubling attributes with vaping but only in battery performance and juice consistency so vape until your heart is content just be safe about it and never leave your juice or your rig in your vehicle keep it on your person this way you can prevent catastrophic situations from occurring.
Health wise; no it doesn't matter. Like what's been said battery performance will drop significantly around 50-65 percent at 0f from my experience.
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