Hi, Alex, and welcome aboard!
Best setting? Each of us will have our own, since each of us vapes in our own style. Power (watt mode)? TC? Straight voltage control? Mechanical?
I'm in the low power group since - for ME - I get what I need to remain an ex-smoker. 1.5 Ω at 8 to 10 watts, depending on flavor. I get enough vapor to continue to fool my brain that I'm smoking, decent throat hit, also part of the process - for ME. And all my flavors (many!) are DIY.
Start your vaping at a setting that at least produces vapor, then work it up in small steps, with "small" relative to the power setting. (I.e., if you're like me at 8 watts, use 1/2 watt steps. If you're up at 40 or 50 watts, maybe 5 or 10 watt steps.) When you get to a step where it seems the flavor (or other performance value) starts to go south, back off a step or two and be happy - you've found the setting for YOUR tastes.
And do bear in mind that different flavors can taste their best at different power settings. I find tobacco flavors will shine at higher levels than fruits and desserts, for example, and so it may be for you.