Oh, they are two very different beasts . . . have 'em both and love 'em both.
The Dura-C has a harsher vape, more reminiscent of a tobacco cigarette. The Kissbox, on the other hand, has a smoother vape, which (imo) allows you to taste the liquid a bit better.
Both have sealed
batteries, so you can drip with them and not worry that flooding your atomizer will ruin your
batteries.
The KB has a much longer body, comprised of FOUR parts--the battery, the switch, the atomizer, and the cart. The KB comes with two different switches--one automatic and the other manual. This allows you to decide which you prefer.
The Dura-C, on the other hand, has a shorter body, comprised of THREE parts--the battery, the atomizer, and the cart. The Dura-C has a manual battery, and the switch is on the battery itself (as opposed to the KB, where the switch is a separate piece).
The Dura-C has a round mouthpiece, while the KB has a whistle-tip.
Personally, I find the Dura-C batteries don't last nearly as long as the KB batteries, but there is a PCC (portable charger) for the Dura-C so that you can charge a battery on the go. Also, both the Dura-C and the KB have USB passthrough batteries so that battery life is essentially a non-issue while at the computer.
Once you get past the size and style difference, I think the biggest difference between the two is just in terms of the vape itself. Like I said at the beginning of this post, the Dura-C has a harsher vape. When I first quit tobacco, I really craved a harsher vape, and the Dura-C came the closest to satisfying that craving. Even now (going on four months tobacco-free), I still like a harsh vape, although I find myself more and more enjoying the smoother vape offered by the KB.
Hope that helps.