Ok I think I got it nailed down lol...
I had my all day vape flavor loaded into the zen at the time I was asked the question. This is the RY5 with menthol which you can get from fsusa. I finally got around to really "playing" with the zenesis. There is a pretty strong menthol in this flavor and, for me, creates a much noticeable throat hit. I actually wanted more vapor with less throat hit so I took a wrap out of my coil... CAUGH! It was tasty, but it hurt. Went back to the 4/5. There is still plenty of vapor this way, i just wanted that little more. I got my Bobas bounty in last night and attempted the 3/4 wrap, as opposed to the stock 4/5, and holy crap! Tons of vapor and the TH was perfect. I guess I just figured out that actually diving in and using different flavors, along with different wraps will provide different experiences lol. So, I think for non menthol "smooth" flavors I will go with the 3/4 and menthol type flavors will be 4/5.
Yea, I should have just wrapped my own coils instead of asking on the forum, but I guess I was just trying to get a quick answer at the time. Thanks for the thorough response creamsteam! Turns out less wraps does, in fact = less resistance = stronger TH+ more vapor.