100% vg in any tank (even the Atlantis subtank) will not function to its utmost. The cotton won't wick up fast enough in order for the coils to burn it off. It's like pouring oil on water, the water can't absorb the oil fast enough therefore the oil remains floating above surface. In a RDA, it's much different because the amount of cotton placed around the coil does not cover the coil, so beings the coil or wire is exposed in the middle, the liquid burns quicker plus an RDA build when it is in sub ohm range automatically vaporizes the liquid because the coil/wire is heated to a higher degree whereas in a tank set up it's quite the opposite especially considering the battery that runs a Nautilus at somewhere between 1.2 ohm to 2.4 ohm or thereabouts is a much smaller amp battery than a 18650 or a 26650 battery, so the battery attempting to vaporize juice that works with the Nautilus, usually the watts are no more than 25 watts or thereabouts will not produce enough power to vaporize or absorb the e liquid fast enough. I once used the Nautilus Mini on a eleaf istick 20 watt with 70vg/30pg and it works fine...but if I had put 100% vg into the tank I would be asking too much from the battery let alone the 20 watt does not sub ohm. In other words, as a quick reply (((smiles))): 100% vg is really only used for the sub ohmers. I have 100% 3 mg in my RDA(s) and it works great (even 6mg). But if you go over 6 mg nicotine with 100% vg your lungs will not be able to handle it. So in my humble opinion, stick with 70vg/30pg for the Nautilus and Nautilus Mini, and when you get into sub ohming on a RDA then the 100% vg juice will come into handy. Hope this helps.