V1. Dry Throat, Sore Throat
Tobacco withdrawal produces a sore throat in some people. It is unknown why this occurs but perhaps cigarette smoke ingredients have some sort of preventative or anaesthetic effect, and stop the throat becoming sore during cigarette use, which it is easy to see could cause it.
Some - but by no means all - suffer from a dry throat, or even a sore throat, when starting to use an e-cigarette due to the drying-out effect of PG.
If a person suffers from both conditions: the tobacco withdrawal sore throat, and the e-cigarette new-user sore throat, then in rare cases a fiercely sore throat can result.
PG is a humectant (attracts, ie 'sucks out' water) and when vaping the back of the throat gets coated. You can find that after sleeping, you wake up with a sore throat. Things that can help are drinking a glass of water before bed, gargling with a mouthwash to cut the PG coating before bed, drinking water throughout the day, using hard candies and drinking liquids with honey liquid through the day to keep your mouth moist - especially if you are a new user.
An alternative for those who experience more throat dryness than normal is to change to a VG-based e-liquid, which normally solves the problem.