4.2 is the highest voltage your battery will be after a complete charge. Your goal in finding the ohms is to get the resistance of the atomizer you're using. To my knowledge, this cannot be done using a calculator. You'll need to use a multimeter to physically test the resistance of the
device you're working with. Knowing the resistance enables you to make an informed decision as to the highest voltage/wattage setting you can go to without "popping" the coil or doing something else to damage the device. The following chart has some good information as to where you shouldn't be in terms of voltage/wattage (wattage is commonly referred to as power):
With respect to the chart above, you can start anywhere from the blues and make your way up, but you should be wary of entering the purples, and when going into the reds and maroons, you need to be as careful as possible so as to prevent any damage.
Edit: To help you better understand, mAh has absolutely nothing to do with much of anything other than telling you approximately how long your battery will last.