You might want to give another type of atomizer a try. I don't think it would hurt the unit ( could be wrong,) but I think you will have a much better vape experience with a different atomizer on the mvp2 _ unit. Didn't the mvp2 come with a iclear atomizer? When I used the mvp2 my unit came with a iclear. If not you can buy them fairly cheaply. Also a protank might be a better choice as well. When I was using my mvp2 I've never tried the ce4 on it.the 510 connection of the mvp2 WILL accept ANY 510 connective aromizer. However you will get a MUCH better experience if you go with a larger atomizer. There are so many to choose from. Also I'm my opinion, a bottom fed atomizer like the protank or I clear, will also give you a bit of a better experience. You can also use something like the nautilus tank.any of these other tanks will give you a much better experience and vape than the ce4 in my opinion. Of course you can use what you l8ke, I just think you will have a much better experience with the mvp2 using a different atomizer. The larger tanks do well with the mvp2. The mvp2 is a great unit and I think you will enjoy it so much more with a better larger atomizer. I really hope this is helpful. I wish you the best. I hope you don't mind me making these suggestions. Good luck on your vaping journey.