Cytisine,better than NRT's

[skoony]

haven't heard of this one before.
Could Seeds of Golden Rain Tree Help Smokers Quit?

regards
mike

 

[sofarsogood]

The drug companies that make nic patches and gum have certainly known of this chemical for many years and might even remember why they didn't develop a treatment with it. The article says the main benefit is lower cost but that doesn't mean much if the treatment doesn't work any better than gum and patches.

Presumably the problem with these types of treatments is relapse. Yesterday, after 6 weeks on zero cigs I was persuading a brother to start vaping. To make a point I smoked one of his cigarettes then declined another and felt no interest in having another (the taste was not what I remember). I've lost interest in cigarettes, even after smoking one. That's way better than "quitting". vaping isn't a treatment, it's a substitute.

 

[Nermal]

vaping isn't a treatment, it's a substitute.

I like the way you put that.

 

[rothenbj]

The drug companies that make nic patches and gum have certainly known of this chemical for many years and might even remember why they didn't develop a treatment with it. The article says the main benefit is lower cost but that doesn't mean much if the treatment doesn't work any better than gum and patches.

Presumably the problem with these types of treatments is relapse. Yesterday, after 6 weeks on zero cigs I was persuading a brother to start vaping. To make a point I smoked one of his cigarettes then declined another and felt no interest in having another (the taste was not what I remember). I've lost interest in cigarettes, even after smoking one. That's way better than "quitting". Vaping isn't a treatment, it's a substitute.

I had the desire to try a cigarette at the 6 month mark of having not a single drag, just to see what they tasted like then. I decided to wait for the year mark. By the time a year passed, I wasn't even interested in a single drag. In about seven weeks it will be 5 years since my last drag on a cigarette and I vape occasionally. Not bad for a 2-3 PAD, 43 year smoker.

 

[csardaz]

Better known as Tabex

 

[DrMA]

Cytisine is a drug with a very similar (perhaps identical?) mode of action to varenicline (Chantix). As such, it probably has the same side-effects.

Pharma has known about this for 40+ years and they never investigated or marketed cytisine because it's very inexpensive and likely un-pattentable.